TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKd: 1nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 1.90nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain olfactory tubercleMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 3.20nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain cortexMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 5.10nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain straitumMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 5.40nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain thalamusMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 5.90nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain olfactory tubercleMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 7.10nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain hippocampusMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKd: 7.60nMAssay Description:Binding affinity to GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 9.10nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain hippocampusMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 9.30nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain straitumMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 9.80nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain cortexMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 15.2nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain thalamusMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKd: 94nMAssay Description:Binding affinity towards human NR2B receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.290nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.350nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.413nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.716nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.838nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 0.940nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.02nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of NMDA receptor-specific [3H]-ifenprodil binding to recombinant human NMDA receptor, NR2B subtype expressed in L cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.40nM ΔG°: -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.40nM ΔG°: -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.42nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.5nM ΔG°: -54.6kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.60nM ΔG°: -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 1.60nM ΔG°: -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation countin...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]ifenprodil from human recombinant GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 2nM ΔG°: -53.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]ifenprodil from Wistar rat GluN2B receptor after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute Of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]ifenprodil from human recombinant GluN2B expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by ...More data for this Ligand-Target Pair