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Report error Found 27 of affinity data for UniProtKB/TrEMBL: P0A031
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079356BDBM50079356(CHEMBL511201)
Affinity DataIC50: 150nMAssay Description:Inhibition of Staphylococcus aureus FTsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079356BDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079356BDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079356BDBM50079356(CHEMBL511201)
Affinity DataIC50: 154nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50589185BDBM50589185(CHEMBL5199894)
Affinity DataKd:  600nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402381BDBM50402381(CHEMBL2207296)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605151BDBM50605151(CHEMBL5188114)
Affinity DataKd:  2.38E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605149BDBM50605149(CHEMBL5200927)
Affinity DataKd:  2.49E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399003BDBM50399003(CHEMBL2180486)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli BL21 (DE3) at 25 degC by fluorescence anisotropy assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605150BDBM50605150(CHEMBL5174791)
Affinity DataKd:  3.84E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605152BDBM50605152(CHEMBL5186593)
Affinity DataKd:  3.86E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ assessed as dissociation constant by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079356BDBM50079356(CHEMBL511201)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402380BDBM50402380(CHEMBL2207300)
Affinity DataKd:  5.40E+3nMAssay Description:Binding affinity to Staphylococcus aureus FtsZ expressed in Escherichia coli cells assessed as dissociation constant by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50203126BDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201769BDBM50201769(CHEMBL3416823)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201769BDBM50201769(CHEMBL3416823)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50320891BDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439496BDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 4.40E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608376BDBM50608376(CHEMBL3416822)
Affinity DataIC50: 5.57E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50439495BDBM50439495(CHEMBL2418095)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608375BDBM50608375(CHEMBL3416821)
Affinity DataIC50: 7.72E+4nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50320891BDBM50320891(9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...)
Affinity DataIC50: 7.74E+4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) preincubated for 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 186046BDBM186046(US9169182, J24)
Affinity DataIC50: 8.80E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608374BDBM50608374(CHEMBL3416820)
Affinity DataIC50: 3.17E+5nMAssay Description:Inhibition of Staphylococcus aureus recombinant FTsZ preincubated for 10 mins followed by compound addition measured after 30 mins by Cytophos phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
Indian Institute of Science Education and Research Bhopal

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50201768BDBM50201768(CHEMBL2413354)
Affinity DataIC50: 3.17E+5nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed