Compile Data Set for Download or QSAR
Report error Found 417 for UniProtKB: Q62968
TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161329BDBM161329(US9163042, 1a | US9051270, 114 | US10087143, Compo...)
Affinity DataIC50: 1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161329BDBM161329(US9163042, 1a | US9051270, 114 | US10087143, Compo...)
Affinity DataIC50: 1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181203BDBM181203(US9139529, 46 | US9783501, Compound 46)
Affinity DataIC50: 1nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50344821BDBM50344821(10-hydroxymethyl-5-imino-(2S)-12,13-dioxa-4,6-diaz...)
Affinity DataKd:  1.80nMAssay Description:Displacement of [3H]saxitoxin from NaV in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181223BDBM181223(US9139529, 66 | US9783501, Compound 66 | US2025011...)
Affinity DataIC50: 2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161373BDBM161373(US9051270, 158 | US10087143, Compound 158 | US9758...)
Affinity DataIC50: 2nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161326BDBM161326(US9163042, 2a | US9051270, 111 | US10087143, Compo...)
Affinity DataIC50: 3nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181163BDBM181163(US9139529, 6 | US9783501, Compound 6)
Affinity DataIC50: 3nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161326BDBM161326(US9163042, 2a | US9051270, 111 | US10087143, Compo...)
Affinity DataIC50: 3nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 186571BDBM186571(US9163042, 1 | US10787472, Compound 1)
Affinity DataIC50: 4nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181161BDBM181161(US9139529, 4 | US9783501, Compound 4)
Affinity DataIC50: 4nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181168BDBM181168(US9139529, 11 | US9783501, Compound 11)
Affinity DataIC50: 5nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161369BDBM161369(US9051270, 154 | US10087143, Compound 154 | US9758...)
Affinity DataIC50: 5nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181165BDBM181165(US9139529, 8 | US9783501, Compound 8)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161328BDBM161328(US9163042, 3a | US9051270, 113 | US10087143, Compo...)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181159BDBM181159(US9139529, 2 | US9783501, Compound 2)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 160984BDBM160984(US9108903, 49)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161328BDBM161328(US9163042, 3a | US9051270, 113 | US10087143, Compo...)
Affinity DataIC50: 6nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161330BDBM161330(US9051270, 115 | US10087143, Compound 115 | US9758...)
Affinity DataIC50: 7nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181190BDBM181190(US9139529, 33 | US9783501, Compound 33)
Affinity DataIC50: 7nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181171BDBM181171(US9139529, 14 | US9783501, Compound 14)
Affinity DataIC50: 7nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181220BDBM181220(US9139529, 63 | US9783501, Compound 63)
Affinity DataIC50: 8nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50329205BDBM50329205(5-(4-chlorophenyl)-N-((2-(piperidin-1-yl)pyridin-3...)
Affinity DataIC50: 8nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50329211BDBM50329211(5-(4-chlorophenyl)-N-(2-methylbenzyl)nicotinamide ...)
Affinity DataIC50: 9nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 160986BDBM160986(US9108903, 51 | US9108903, 76)
Affinity DataIC50: 9nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161368BDBM161368(US9051270, 153 | US10087143, Compound 153 | US9758...)
Affinity DataIC50: 10nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 160947BDBM160947(US9108903, 12)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161294BDBM161294(US9163042, 5a | US9051270, 82 | US9051270, 79 | US...)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181222BDBM181222(US9139529, 65 | US9783501, Compound 65)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 160967BDBM160967(US9108903, 32)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161245BDBM161245(US9163042, 4a | US9051270, 30 | US10087143, Compou...)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181218BDBM181218(US9139529, 61 | US9783501, Compound 61)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161370BDBM161370(US9051270, 155 | US10087143, Compound 155 | US9758...)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 160953BDBM160953(US9108903, 18)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161294BDBM161294(US9163042, 5a | US9051270, 82 | US9051270, 79 | US...)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161245BDBM161245(US9163042, 4a | US9051270, 30 | US10087143, Compou...)
Affinity DataIC50: 11nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 160986BDBM160986(US9108903, 51 | US9108903, 76)
Affinity DataIC50: 12nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161303BDBM161303(US9163042, 6a | US9051270, 88 | US10087143, Compou...)
Affinity DataIC50: 12nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 50330949BDBM50330949(N-(3,5-Dimethylphenyl)-6-(4-ethoxyphenyl)-pyrazine...)
Affinity DataIC50: 12nMAssay Description:Inhibition of tetrodotoxin-resistant NaV1.8 in rat dorsal root ganglion neurons at holding potential -100 mV by whole-cell patch clamp electrophysiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 160976BDBM160976(US9108903, 41)
Affinity DataIC50: 12nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161303BDBM161303(US9163042, 6a | US9051270, 88 | US10087143, Compou...)
Affinity DataIC50: 12nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161287BDBM161287(US9163042, 8a | US9051270, 73 | US9051270, 72 | US...)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181162BDBM181162(US9139529, 5 | US9783501, Compound 5)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181225BDBM181225(US9139529, 68 | US9783501, Compound 68)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161285BDBM161285(US9163042, 7a | US9051270, 70 | US9758483, Compoun...)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161287BDBM161287(US9163042, 8a | US9051270, 73 | US9051270, 72 | US...)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161285BDBM161285(US9163042, 7a | US9051270, 70 | US9758483, Compoun...)
Affinity DataIC50: 13nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181166BDBM181166(US9139529, 9 | US9783501, Compound 9)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 161225BDBM161225(US9163042, 9a | US9051270, 10 | US10087143, Compou...)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 181228BDBM181228(US9139529, 71 | US9783501, Compound 71)
Affinity DataIC50: 14nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

Displayed 1 to 50 (of 417 total ) | Next | Last >>
Jump to: