Compile Data Set for Download or QSAR
Report error Found 34 of affinity data for UniProtKB/TrEMBL: Q9ERM3
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385398BDBM50385398(CHEMBL2036730)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27950BDBM27950(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27947BDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The assay mixture contains test compound, membrane protein, and 1,2 dioleoyl-sn-glycerol in a 96-deep well plate. The reaction was started by adding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355142BDBM50355142(CHEMBL1835919)
Affinity DataIC50: 64nMAssay Description:Inhibition of rat DGAT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 90nMAssay Description:Inhibition of DGAT1 in rat adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341760BDBM50341760(2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Aci...)
Affinity DataIC50: 120nMAssay Description:Inhibition of rat DGAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287311BDBM50287311(CHEMBL4176968)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399710BDBM50399710(CHEMBL2178953)
Affinity DataIC50: 150nMAssay Description:Inhibition of DGAT1 in rat adipose tissue assessed as reduction in triacylglycerol synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287313BDBM50287313(CHEMBL4168991)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287389BDBM50287389(CHEMBL4174767)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287320BDBM50287320(CHEMBL4166344)
Affinity DataIC50: 631nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50287330BDBM50287330(CHEMBL4166868)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant rat DGAT1 expressed in baculovirus infected Sf9 insect microsomal membranes using C10-DAG and [3H]-labelled decanoyl-CoA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27947BDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402756BDBM50402756(CHEMBL2207805)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402753BDBM50402753(CHEMBL2207808)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402748BDBM50402748(CHEMBL2207794)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402752BDBM50402752(CHEMBL2207809)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50208612BDBM50208612(kurarinone | (-)-kurarinone | (2S)-2-(2,4-dihydrox...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402762BDBM50402762(CHEMBL2207799)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402754BDBM50402754(CHEMBL2207807)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402757BDBM50402757(CHEMBL2207804)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402763BDBM50402763(CHEMBL2207798)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402767BDBM50402767(CHEMBL2205735)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402755BDBM50402755(CHEMBL2207806)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402761BDBM50402761(CHEMBL2207800)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402758BDBM50402758(CHEMBL2207803)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402760BDBM50402760(CHEMBL2207801)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402759BDBM50402759(CHEMBL2207802)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402764BDBM50402764(CHEMBL2207797)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402766BDBM50402766(CHEMBL2207795)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402750BDBM50402750(CHEMBL2207811)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402765BDBM50402765(CHEMBL2207796)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402749BDBM50402749(CHEMBL2207812)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402751BDBM50402751(CHEMBL2207810)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DGAT in rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed