BDBM10881 CHEMBL288100::MZA3::Methazolamide::Methazolamide (MZA)::Methazolamide, MZA::N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide::Sulfonamide, 2::cid_4100::sulfonamide 2

SMILES CC(=O)N=c1sc(nn1C)S(N)(=O)=O

InChI Key InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N

Data  290 KI  9 IC50  2 EC50

PDB links: 7 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 77 hits for monomerid = 10881   

TargetCarbonic anhydrase 3(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  1.10nMAssay Description:Inhibition of human carbonic anhydrase 3More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 7(Homo sapiens (Human))
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LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  2.10nMAssay Description:Inhibition of human carbonic anhydrase 7More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 7(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  2.10nMAssay Description:Inhibition of human recombinant full length CA7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 7(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  2.10nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 12(Homo sapiens (Human))
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LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  3.40nMAssay Description:Inhibition of human carbonic anhydrase 12More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 12(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  3.40nMAssay Description:Inhibition of human recombinant CA12 catalytic domain by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 6(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  10nMAssay Description:Inhibition of human carbonic anhydrase 6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
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TargetCarbonic anhydrase 6(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant full length CA6 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of human cloned full length carbonic anhydrase 2 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant full length CA2 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant CA2 cytosolic isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Compound was evaluated for inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:In vitro inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Ki value against human carbonic anhydrase IIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  14nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

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TargetCarbonic anhydrase 13(Mus musculus (mouse))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  19nMAssay Description:Ki value against murine carbonic anhydrase XIIIMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  19nMAssay Description:Inhibition of mouse carbonic anhydrase 13More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  19nMAssay Description:Inhibition of mouse recombinant full length CA13 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

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TargetCarbonic anhydrase 9(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Inhibitory activity against human carbonic anhydrase IXMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase isozyme IX, by CO2 hydrase assay method.More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Compound was evaluated for inhibition against human carbonic anhydrase IXMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Inhibitory constant against human Carbonic anhydrase IXMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IXMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  27nMAssay Description:Inhibition of human cloned carbonic anhydrase 9 by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  36nMAssay Description:Compound was evaluated for inhibition against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  36nMAssay Description:Inhibitory activity against carbonic anhydrase isolated from bovine lung microsome (bCA IV)More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  36nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (bCAIV)More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 4(Bos taurus (bovine))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  36nMAssay Description:Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method.More data for this Ligand-Target Pair

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TargetCarbonic anhydrase 14(Homo sapiens (Human))
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LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant full length CA14 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

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TargetCarbonic anhydrase 14(Homo sapiens (Human))
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LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  43nMAssay Description:Inhibition of human carbonic anhydrase 14More data for this Ligand-Target Pair

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TargetCarbonic anhydrase 1(Homo sapiens (Human))
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LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Compound was evaluated for inhibition against human carbonic anhydrase IMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
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LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Inhibitory constant against human Carbonic anhydrase IMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

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TargetCarbonic anhydrase 1(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Inhibitory activity against human carbonic anhydrase I (hCAI)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Ki value against human carbonic anhydrase IMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Inhibition of human carbonic anhydrase 1More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
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Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant full length CA1 expressed in Escherichia coli BL21 (DE3) by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM10881(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Copy SMILESCopy InChI

Affinity DataKi:  50nMAssay Description:Inhibition of human recombinant CA1 cytosolic isoform by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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