BDBM17657 (2S)-2-aminopentanedioic acid::(S)-Glu::D-Glutamate::Glutamate::L-Glu::L-Glutamate::L-Glutamic acid::L-[14C(U)]glutamate::L-gluatmate
SMILES N[C@@H](CCC(O)=O)C(O)=O
InChI Key InChIKey=WHUUTDBJXJRKMK-VKHMYHEASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 40 hits for monomerid = 17657
Affinity DataKi: 140nMAssay Description:Displacement of [3H]SYM2081 from rat iGluR5 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Displacement of [3H]quisqualate from mGluR1 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [3H]AMPA from rat iGluR2 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Displacement of [3H]SYM2081 from rat iGluR6 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 390nMAssay Description:Binding affinity to mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Displacement of [3H]SYM2081 from rat iGluR7 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of [3H]LAP4 from mGluR4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.40E+3nMAssay Description:Displacement of [3H]Quisqualate from human mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Displacement of [3H]LY341495 from mGluR2 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.40E+3nMAssay Description:Antagonistic activity against stimulation of GTP (gamma) 35 S binding by glutamate in membranes from CHO cells expressing human mGluR2More data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+3nMAssay Description:Functional activity at rat mGluR4More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Activity at rat mGluR5 by measuring intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at human mGluR7 by measuring cAMP formation in BHK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30E+3nMAssay Description:Activity at rat mGluR1 by measuring intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.60E+3nMAssay Description:Activity at rat mGluR6 by measuring cAMP formation in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+4nMAssay Description:Activity at human mGluR2 from BHK cells in [35S]GTP-gamma-S stimulation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Agonist activity in rat at Metabotropic glutamate receptor 8 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Agonist activity in rat at Metabotropic glutamate receptor 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity in rat at Metabotropic glutamate receptor 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Activity at rat recombinant mGluR5 expressed in CHO cells assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at human recombinant mGluR7 expressed in BHK cells assessed as cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30E+3nMAssay Description:Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
Affinity DataEC50: 7.60E+3nMAssay Description:Activity at rat recombinant mGluR6 expressed in CHO cells assessed as cAMP productionMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+4nMAssay Description:Activity at human recombinant mGluR2 expressed in BHK cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+3nMAssay Description:Agonist activity at rat recombinant mGluR4 expressed in BHK cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.50E+4nMAssay Description:Activity at rat cloned iGluR1 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+5nMAssay Description:Activity at rat cloned iGluR2 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+5nMAssay Description:Activity at rat cloned iGluR3 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+4nMAssay Description:Activity at rat cloned iGluR4 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+5nMAssay Description:Activity at rat cloned iGluR5 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.60E+4nMAssay Description:Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+4nMAssay Description:Activity at recombinant iGluR2 receptor expressed in Xenopus laevis oocytes using holding potential of -15 to -20 mV by TEVC electrophysiologyMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Agonist activity at rat NR1/NR2A receptor expressed in BHK21 cells assessed as change in intracellular calcium levels by FLIPR assayMore data for this Ligand-Target Pair