BDBM50114024 CHEMBL3605413

SMILES Nc1ccc(cc1F)C(=O)NC1(CCCCC1)C(=O)NCC#N

InChI Key InChIKey=NEJGUCSKQVFSJQ-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50114024   

TargetCathepsin K(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114024(CHEMBL3605413)
Affinity DataKi:  22nMAssay Description:Inhibition of human cathepsin-K using Z-Gly-Pro-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProcathepsin L(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114024(CHEMBL3605413)
Affinity DataKi:  720nMAssay Description:Inhibition of human cathepsin-L using Z-Phe-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Human)
National Institute of Chemistry

Curated by ChEMBL
LigandPNGBDBM50114024(CHEMBL3605413)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human cathepsin-S using Z-Phe-Val-Arg-AMC as substrate preincubated for 30 mins measured after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed