BDBM50297825 5-(2-methyl-5-(3-(trifluoromethyl)phenylcarbamoyl)phenylamino)nicotinamide::5-[(2-Methyl-5-{[3- (trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide (1)::5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide::CHEMBL552425

SMILES Cc1ccc(cc1Nc1cncc(c1)C(N)=O)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=SAAYRHKJHDIDPH-UHFFFAOYSA-N

Data  5 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297825   

TargetEphrin type-B receptor 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50297825(5-(2-methyl-5-(3-(trifluoromethyl)phenylcarbamoyl)...)
Affinity DataEC50:  40nMAssay Description:Inhibition of EphB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50297825(5-(2-methyl-5-(3-(trifluoromethyl)phenylcarbamoyl)...)
Affinity DataEC50:  100nMAssay Description:Inhibition of ephrinB1-induced autophosphorylation of EphB2 expressed in human U87 cells after 1 hr by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed