BDBM50393756 CHEMBL2159198
SMILES Cc1nc2cnc3[nH]ccc3c2n1C1CCCCC1
InChI Key InChIKey=XXXPSYBQNILIFB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50393756
Affinity DataEC50: 6.60E+3nMAssay Description:Inhibition of JAK2 in human UT7 cells assessed as inhibition of Epo-dependent STAT5 phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center
Curated by ChEMBL
Abbott Bioresearch Center
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of KDR (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL6-dependent STAT3 phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of JAK2 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy tranfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PKCalpha (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATPMore data for this Ligand-Target Pair