BDBM8960 (+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one::2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one::Aricept::Aricept odt::CHEMBL1678::CHEMBL2337271::CHEMBL502::DONEPEZIL HYDROCHLORIDE::Donepezil::Donepzil::E2020::US8999994, Donepezil::US9346818, DPH::US9586925, Donepezil::US9663465, Donepezil
SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
InChI Key InChIKey=ADEBPBSSDYVVLD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 8960
Affinity DataKi: 10nMAssay Description:Mixed inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.14E+3nMAssay Description:Non-competitive inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human plasma AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:In vitro inhibition of Torpedo californica acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against acetylcholinesterase (AChE) from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory concentration against Butyrylcholinesterase (BuChE) from human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of acetylcholinesterase from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of butyrylcholinesterase from human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:In vitro inhibition of electric eel acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of equine butyrylcholinesterase using butyrylthicholine as substrate incubated for 20 mins prior to substrate addition measured after 3 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of bovine acetylcholinesterase using acetylcholine iodide as substrate incubated for 20 mins prior to substrate addition meausred after 3 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair