BDBM8960 (+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one::2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one::Aricept::Aricept odt::CHEMBL1678::CHEMBL2337271::CHEMBL502::DONEPEZIL HYDROCHLORIDE::Donepezil::Donepzil::E2020::US8999994, Donepezil::US9346818, DPH::US9586925, Donepezil::US9663465, Donepezil
SMILES COc1cc2CC(CC3CCN(Cc4ccccc4)CC3)C(=O)c2cc1OC
InChI Key InChIKey=ADEBPBSSDYVVLD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 8960
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of electric eel ACHE preincubated for 6 mins followed by addition of acetylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of equine BCHE preincubated for 6 mins followed by addition of S-butyrylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of human erythrocyte ACHE preincubated for 6 mins followed by addition of acetylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.76E+3nMAssay Description:Inhibition of human serum BCHE preincubated for 6 mins followed by addition of S-butyrylcholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair