Compile Data Set for Download or QSAR
Report error Found 258 Enz. Inhib. hit(s) with Target = 'Estrogen receptor [298-554]'
TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521421BDBM521421(6-(2,4- dichlorophenyl)- 1-fluoro-5-[6- [(3S)-1-(3...)
Affinity DataIC50: 0.400nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521255BDBM521255(3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[6- [(3S)-1-(3...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521262BDBM521262(6-(6-ethoxy-2- fluoro-3- pyridyl)-5-[4- [[(3S)-1-(...)
Affinity DataIC50: 0.5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521413BDBM521413(6-(2-fluoro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...)
Affinity DataIC50: 0.600nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521384BDBM521384(4-(6-ethoxy-2- fluoro-3- pyridyl)-5-[6- [(3S)-1-(3...)
Affinity DataIC50: 0.600nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521382BDBM521382(4-(2-chloro-4- methyl-phenyl)- 5-[6-[(3S)-1-(3- fl...)
Affinity DataIC50: 0.700nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521428BDBM521428(6-(6-ethoxy-2- fluoro-3- pyridyl)-1- fluoro-5-[6- ...)
Affinity DataIC50: 0.700nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521418BDBM521418(6-(2,2- dimethylindolin- 5-yl)-5-[6-[(3S)- 1-(3- f...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521334BDBM521334(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521377BDBM521377(4-(2,2-dimethyl- 3H-benzofuran- 5-yl)-5-[4-[(3S)- ...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521378BDBM521378(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521261BDBM521261(6-(2,4- dichlorophenyl)- 5-[4-[[(3S)-1- (3- fluoro...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521369BDBM521369(4-(2,2-difluoro- 1,3- benzodioxol-5- yl)-5-[4-[(3S...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521381BDBM521381(4-(2,4- dichlorophenyl)- 5-[(6-[(3S)-1-(3- fluorop...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521221BDBM521221(3-(2-fluoro-6- methoxy-3- pyridyl)-4-[4- [(3S)-1-(...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521360BDBM521360(4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521254BDBM521254(3-(2-fluoro-4- methyl-phenyl)- 4-[6-[(3S)-1-(3- fl...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521425BDBM521425(6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-1- fluo...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521362BDBM521362(4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521394BDBM521394(4-[4- (fluoromethoxy) phenyl]-5-[4- [(3S)-1-(3- fl...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521373BDBM521373(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521374BDBM521374(4-(2,2- dimethylindolin- 5-yl)-5-[4-[(3S)- 1-(3- f...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521417BDBM521417(6-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...)
Affinity DataIC50: 1nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521363BDBM521363(4-(6-ethoxy-2- fluoro-3- pyridyl)-5-[4- [(3S)-1-(3...)
Affinity DataIC50: 1.5nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521354BDBM521354(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521333BDBM521333(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521297BDBM521297(US11149031, Example 189 | 4-(2-fluoro-4- methoxy- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521270BDBM521270(4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521345BDBM521345(4-(2-fluoro-4- hydroxy- phenyl)-5-[4- [(3S)-1-(3- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521399BDBM521399(4-(6-amino-2- fluoro-3- pyridyl)-5-[4- [(3S)-1-(3-...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521229BDBM521229(3-(3-chloro-2- ethoxy-4- pyridyl)-4-[4- [(3S)-1-(3...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521422BDBM521422(6-(4-ethoxy- 2,3-difluoro- phenyl)-5-[2- [(3S)-1-(...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521295BDBM521295(4-(4-ethoxy-2- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521296BDBM521296(4-(benzofuran- 5-yl)-5-[4-[(3S)- 1-(3- fluoropropy...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521297BDBM521297(US11149031, Example 189 | 4-(2-fluoro-4- methoxy- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521383BDBM521383(4-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[6- [...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521203BDBM521203(3-(6-ethoxy-2- fluoro-3- pyridyl)-4-[4- [(3S)-1-(3...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521267BDBM521267(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521182BDBM521182(7-(2-fluoro-4- hydroxy- phenyl)-8-[4- [(3S)-1-(3- ...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521385BDBM521385(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 2nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521361BDBM521361(4-(4-ethoxy-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 2.90nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521344BDBM521344(4-(2-chloro-3- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521376BDBM521376(4-[4- (ethylamino)-2- fluoro-phenyl]- 5-[4-[(3S)-...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521420BDBM521420(6-(2-fluoro-4- methyl-phenyl)- 5-[2-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521335BDBM521335(4-(2-chloro-4- fluoro-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521367BDBM521367(4-[4- (difluoromethoxy)- 3-fluoro- phenyl]-5-[4- [...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521303BDBM521303(4-(6-ethoxy-3- pyridyl)-5-[4- [(3S)-1-(3- fluoropr...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521336BDBM521336(5-[4-[(3S)-1-(3- fluoropropyl)pyr- rolidin-3- yl]o...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521414BDBM521414(6-(2,4- dichlorophenyl)- 5-[2-[(3S)-1-(3- fluoropr...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetEstrogen receptor [298-554](Human)
Sanofi

US Patent
LigandChemical structure of BindingDB Monomer ID 521340BDBM521340(4-(2-fluoro-4- methyl-phenyl)- 5-[4-[(3S)-1-(3- fl...)
Affinity DataIC50: 3nMAssay Description:Antagonistic potency of compounds was evaluated using LanthaScreen TR-FRET ERα Coactivator Assay (ThermoFisher) with modifications. It is a comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

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