Compile Data Set for Download or QSAR
Report error Found 164 Enz. Inhib. hit(s) with Target = 'Mas-related G-protein coupled receptor member X1'
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412987(CHEMBL475965)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605928(CHEMBL5195160)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340753(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605927(CHEMBL5172913)
Affinity DataEC50:  14nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340743(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412988(CHEMBL477008)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340744(N-benzyl-2-(4-(2-(4-chlorophenethylamino)pyrimidin...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412989(CHEMBL474473)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340745(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412987(CHEMBL475965)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human MrgX1 transfected in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605956(CHEMBL5205606)
Affinity DataEC50:  31nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340746(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM224021(BAM8-22 | VGRPEWWMDYQKRYG)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human MrgprX1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM224021(BAM8-22 | VGRPEWWMDYQKRYG)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human MrgX1 transfected in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509101(CHEMBL4460098)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340753(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human MrgX1 transfected in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412986(CHEMBL474474)
Affinity DataEC50:  52nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605947(CHEMBL5202767)
Affinity DataEC50:  54nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605952(CHEMBL5185447)
Affinity DataEC50:  55nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413339(CHEMBL502132)
Affinity DataEC50:  63.1nMAssay Description:Agonist activity at human MrgX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605954(CHEMBL5194692)
Affinity DataEC50:  69nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340750(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 77nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605955(CHEMBL5177145)
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413002(CHEMBL475077)
Affinity DataEC50:  81nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340747(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 88nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605945(CHEMBL5171656)
Affinity DataEC50:  98nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50583471(CHEMBL5084093)
Affinity DataEC50:  100nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 transfected in HEK293 cells in presence of BAM8-22 by Fulo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509099(CHEMBL4565294)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605941(CHEMBL5200001)
Affinity DataEC50:  103nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413004(CHEMBL448975)
Affinity DataEC50:  107nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340751(N-((3-bromopyridin-4-yl)methyl)-2-(4-(2-(4-chlorop...)
Affinity DataIC50: 108nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413003(CHEMBL475282)
Affinity DataEC50:  123nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605929(CHEMBL5177388)
Affinity DataEC50:  124nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412985(CHEMBL458220)
Affinity DataEC50:  126nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412999(CHEMBL449189)
Affinity DataEC50:  132nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412996(CHEMBL477432)
Affinity DataEC50:  145nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509106(CHEMBL4455263)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509097(CHEMBL4541091)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605944(CHEMBL5208855)
Affinity DataEC50:  173nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413334(CHEMBL505263)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human MrgX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605953(CHEMBL5191110)
Affinity DataEC50:  206nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605943(CHEMBL5205025)
Affinity DataEC50:  217nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50583457(CHEMBL5080027)
Affinity DataEC50:  220nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 transfected in HEK293 cells in presence of BAM8-22 by Fulo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50583470(CHEMBL5081104)
Affinity DataEC50:  230nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 transfected in HEK293 cells in presence of BAM8-22 by Fulo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50340748(2-(4-(2-(4-chlorophenethylamino)pyrimidin-4-yl)pip...)
Affinity DataIC50: 244nMAssay Description:Antagonist activity at SNSR4 in human HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Mouse)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM224021(BAM8-22 | VGRPEWWMDYQKRYG)
Affinity DataEC50:  251nMAssay Description:Agonist activity at mouse MrgC11 transfected in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50605940(CHEMBL5203677)
Affinity DataEC50:  285nMAssay Description:Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413000(CHEMBL451657)
Affinity DataEC50:  288nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50509093(CHEMBL4444915)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMas-related G-protein coupled receptor member X1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413005(CHEMBL476627)
Affinity DataEC50:  295nMAssay Description:Agonist activity at human MrgX1 receptor expressed in HEK293 cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
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