Compile Data Set for Download or QSAR
Report error Found 5818 Enz. Inhib. hit(s) with Target = 'Prostaglandin D2 receptor'
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50: 0.0120nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50397638(CHEMBL2181748)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of CRTH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417722(CHEMBL1644207)
Affinity DataIC50: 0.0200nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205275([(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfony...)
Affinity DataKd:  0.0300nMAssay Description:Binding affinity to human DP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417777(CHEMBL1644214)
Affinity DataIC50: 0.0501nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312907(2-(4-(4-chlorophenyl)-2-(diphenylamino)thiazol-5-y...)
Affinity DataIC50: 0.0720nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312909(2-(2-(diphenylamino)-4-(3-fluorophenyl)thiazol-5-y...)
Affinity DataIC50: 0.0790nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312915(2-(2-(1,1-diphenylethyl)-4-(4-fluorophenyl)thiazol...)
Affinity DataIC50: 0.0850nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50205275([(3R)-4-(4-chlorobenzyl)-7-fluoro-5-(methylsulfony...)
Affinity DataIC50: 0.0900nMAssay Description:Activity at human DP receptor in washed platelets assessed as inhibition of PGD2-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312908(2-(2-(diphenylamino)-4-(4-fluorophenyl)thiazol-5-y...)
Affinity DataIC50: 0.0980nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50397639(CHEMBL2181751 | US8791272, 2.47)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127296(US8791272, 17.1)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM196955(US9206164, 19)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50344999(2-(2'-chloro-4'-(N-methylmethylsulfonamido)-5-(tri...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127173(US8791272, 2.50)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124844(US8759386, 41)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124845(US8759386, 42)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124852(US8759386, 49)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM197024(US9206164, 88 | US9206164, 98)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124817(US8759386, 14)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127191(US8791272, 3.9)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124821(US8759386, 18)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127194(US8791272, 3.12)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124858(US8759386, 55)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM155041(US9000044, 60)
Affinity DataIC50: 0.100nMAssay Description:Cell Culture Conditions: CHO-K1 cells previously transfected with G-alpha 16 were subsequently transfected with the human CRTH2 receptor and the neom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2015
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124832(US8759386, 29)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50417721(CHEMBL1644206)
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at prostaglandin D2 receptor in human LS174T cells assessed as inhibition of PGD2-induced cAMP accumulation after 15 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124831(US8759386, 28)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127166(US8791272, 2.42)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor(Human)
Sanofi Aventis Us

Curated by ChEMBL
LigandPNGBDBM50277668((R)-2-(9-(3,4-dichlorophenylthio)-1-isopropyl-7,8-...)
Affinity DataIC50: 0.140nMAssay Description:Antagonist activity at DP1 in washed human platelet assessed as inhibition of PGD2-induced [125I]cAMP production preincubated 10 mins before PGD2 cha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM196956(US9206164, 20)
Affinity DataKi:  0.200nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124806(US8759386, 3)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM196952(US9206164, 16)
Affinity DataKi:  0.200nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124815(US8759386, 12)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124814(US8759386, 11)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124813(US8759386, 10)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50397643(CHEMBL2181803)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]PGD2 from CRTH2 expressed in HEK293 cells after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124822(US8759386, 19)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124828(US8759386, 25)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127164(US8791272, 2.40)
Affinity DataKi:  0.200nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50344995(2-(5'-cyano-2'-methyl-5-(trifluoromethyl)biphenyl-...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50344996(2-(5'-cyano-2'-fluoro-5-(trifluoromethyl)biphenyl-...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124825(US8759386, 22)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50344993(2-(2'-chloro-4'-(methylsulfonyl)-5-(trifluoromethy...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127104(US8791272, 1.15)
Affinity DataKi:  0.200nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM127165(US8791272, 2.41)
Affinity DataKi:  0.200nMpH: 7.4Assay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124835(US8759386, 32)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124834(US8759386, 31)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312917(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM124839(US8759386, 36)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

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