Compile Data Set for Download or QSAR
Report error Found 301 Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein [H232R]'
TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM577477(US11472830, Cpd No. 9)
Affinity DataKd:  0.195nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM457787(US10738074, Example 18)
Affinity DataEC50:  0.400nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573927(US11453697, Example 97 | 2-amino-9-[(2R,5R,7R,8R,1...)
Affinity DataEC50:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM490790(US10968242, Example 17 Peak 2)
Affinity DataKd:  0.5nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573849(US11453697, Example 13 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50:  0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573838(US11453697, Example 2 | US11453697, Example 7 | (5...)
Affinity DataEC50:  0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573930(US11453697, Example 100 | US11453697, Example 101 ...)
Affinity DataEC50:  1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574013(US11453697, Example 103 | US11453697, Example 105 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574093(US11453697, Example 221 | 5-amino-3- [(5R,7R,8R,12...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574016(US11453697, Example 106 | US11453697, Example 107 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574032(US11453697, Example 157 | 2-amino-9-[(5R,7R,8S,12a...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574030(US11453697, Example 155 | US11453697, Example 156 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574030(US11453697, Example 155 | US11453697, Example 156 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM457797(US10738074, Example 34)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM457804(3,3'-[(1S,6R,8R,9S,14R,16R,17R,18R)-17,18- difluor...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM490777(US10968242, Example 3 Peak 4)
Affinity DataKd:  1nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM457792(US10738074, Example 25 | 9,9′-[(1R,6R,8R,9R,...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM490791(US10968242, Example 18 | 9-((4S,6R,7S,11aR,13R,14R...)
Affinity DataKd:  1nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573838(US11453697, Example 2 | US11453697, Example 7 | (5...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573877(US11453697, Example 72 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM457789(US10738074, Example 19)
Affinity DataEC50:  1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM457798(US10738074, Example 22 | US10738074, Example 23 | ...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573919(US11453697, Example 89 | 2-amino-9-[(2R,5R,7R,8R,1...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573954(US11453697, Example 139 | 2-amino-9-[(5S,7R,8R,12a...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574056(US11453697, Example 184 | 5-amino-3-[(5S,7R,8R,12a...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM577472(US11472830, Cpd No. 4)
Affinity DataKd:  1nMAssay Description:Thermofluor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574116(US11453697, Example 248 | US11453697, Example 249 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574116(US11453697, Example 248 | US11453697, Example 249 ...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573971(US11453697, Example 247)
Affinity DataEC50:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574112(US11453697, Example 240 | US11453697, Example 242 ...)
Affinity DataEC50:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM457798(US10738074, Example 22 | US10738074, Example 23 | ...)
Affinity DataEC50:  1.20nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573954(US11453697, Example 139 | 2-amino-9-[(5S,7R,8R,12a...)
Affinity DataEC50:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574069(US11453697, Example 197 | 5-amino-3- [(5R,7R,8S,12...)
Affinity DataEC50:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573850(US11453697, Example 14 | 2-amino-9- [(5S,7R,8R,12a...)
Affinity DataEC50:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574079(US11453697, Example 207 | 5-amino-3-[(5R,7R,8S,112...)
Affinity DataEC50:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573856(US11453697, Example 20)
Affinity DataEC50:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573857(US11453697, Example 21 | 2-amino-9-[(5S,7R,8R,12aR...)
Affinity DataEC50:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573841(US11453697, Example 5 | (5R,7R,8S,12aR,14R,15R,15a...)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574125(US11453697, Example 257 | US11453697, Example 259 ...)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM577478(US11472830, Cpd No. 10)
Affinity DataKd:  1.58nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573933(US11453697, Example 117 | US11453697, Example 118 ...)
Affinity DataEC50:  1.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573933(US11453697, Example 117 | US11453697, Example 118 ...)
Affinity DataEC50:  1.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573926(US11453697, Example 96 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50:  1.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573923(US11453697, Example 93 | 2-amino-9- [(5R,7R,8R,12a...)
Affinity DataEC50:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574134(US11453697, Example 266 | 2-amino-9-[(5R,7R,8R,12a...)
Affinity DataEC50:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573916(US11453697, Example 86 | 2-amino-9-[(2R,5S,7R,8R,1...)
Affinity DataEC50:  2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573916(US11453697, Example 86 | 2-amino-9-[(2R,5S,7R,8R,1...)
Affinity DataEC50:  2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM490794(US10968242, Example 19 Peak 3)
Affinity DataKd:  2nMAssay Description:Surface plasmon resonance (SPR) STING agonist binding studies were carried out using a Biacore T200 instrument (GE Healthcare) at 4° C. in a 150 mM K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2021
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](Human)
Janssen Biotech

US Patent
LigandPNGBDBM577472(US11472830, Cpd No. 4)
Affinity DataKd:  2nMAssay Description:Compounds were analyzed on an 5200 biacore SPR instrument (GE Healthcare). E.coli produced truncated STING protein was immobilized on a series S stre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574086(US11453697, Example 214 | US11453697, Example 217 ...)
Affinity DataEC50:  2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

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