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Found 293 with Last Name = 'lamers' and Initial = 'a'
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547789(CHEMBL4794209)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547752(CHEMBL4797113)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547793(CHEMBL4741218)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547769(CHEMBL4758144)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547790(CHEMBL4754478)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547765(CHEMBL4783572)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547766(CHEMBL4788385)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547751(CHEMBL4755779)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547775(CHEMBL4742646)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537077(US11247971, Cmpd ID 400)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489090(2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3- ((tetrah...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489091(2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3- ((tetrah...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489160(2-(3-(3-(tert- butylcarbamoyl)-4- fluorophenyl)-5-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569440(CHEMBL4877988 | US11752138, Compound 152)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM536955(US11247971, Cmpd ID 278)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489161(2-(3-(3- (benzylcarbamoyl)-4- fluorophenyl)-5- (cy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489092(2-(3-(3- cydopropoxy-4- fluorophenyl)-5- (cyclopro...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547778(CHEMBL4761452)
Affinity DataIC50:  10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547767(CHEMBL4761967)
Affinity DataIC50:  10nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537013(US11247971, Cmpd ID 336)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537072(US11247971, Cmpd ID 395)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537071(US11247971, Cmpd ID 394)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489085(2-(3-(3- phenoxyphenyl)-4-(4- sulfamoylbenzyl)- 1H...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537074(US11247971, Cmpd ID 397)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537017(US11247971, Cmpd ID 340)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489083(2-(3-(3-((3- methoxybenzyl)oxy)phenyl)- 4-(4- sulf...)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489147(2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3-((3- fluo...)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569441(CHEMBL4875236)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489093(2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3-((5- (tri...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489086(2-(3-(3-(pyridin-3- ylmethoxy)phenyl)-4- (4-sulfam...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547764(CHEMBL4740457)
Affinity DataIC50:  24nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547787(CHEMBL4797527)
Affinity DataIC50:  24nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569434(CHEMBL4854797)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489129(2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3-(p- tolyl...)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569438(CHEMBL4847591)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489128(2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3-(3- fluor...)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569433(CHEMBL4857703)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547780(CHEMBL4751598)
Affinity DataIC50:  30nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM489127(2-(5- (cyclopropylmethyl)- 3-(4-fluoro-3- phenoxyp...)
Affinity DataIC50:  34nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569439(CHEMBL4869869 | US11752138, Compound 158)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547782(CHEMBL4745282)
Affinity DataIC50:  38nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569435(CHEMBL4863968)
Affinity DataIC50:  39nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50569436(CHEMBL4879296)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM537069(US11247971, Cmpd ID 392)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547753(CHEMBL4744076)
Affinity DataIC50:  47nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547763(CHEMBL4793775)
Affinity DataIC50:  49nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547760(CHEMBL4763230)
Affinity DataIC50:  50nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547779(CHEMBL4793092)
Affinity DataIC50:  50nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547769(CHEMBL4758144)
Affinity DataIC50:  54nMAssay Description:Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Janssen Pharmaceutica N. V.

Curated by ChEMBL
LigandPNGBDBM50547751(CHEMBL4755779)
Affinity DataIC50:  56nMAssay Description:Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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