Affinity DataIC50: 0.700nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair