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TargetSimilar to alpha-tubulin isoform 1(Bovine)
Minia University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataKi:  140nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504214(CHEMBL4530425)
Affinity DataKi:  150nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504215(CHEMBL4463939)
Affinity DataKi:  260nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533526(jm2c00120, Compound 25)
Affinity DataIC50:  19nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533538(jm2c00120, Compound 35)
Affinity DataIC50:  30nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533519(jm2c00120, Compound 18)
Affinity DataIC50:  38nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533520(jm2c00120, Compound 19)
Affinity DataIC50:  44nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: <50nMAssay Description:Inhibition of N-terminal His6-tagged human RNA-N7 MTase expressed in Escherichia coli using GpppAC4 and [3H]SAM as substrate preincubated with enzyme...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533535(jm2c00120, Compound 32)
Affinity DataIC50:  56nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152597(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-nitrophenyl...)
Affinity DataIC50:  77nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533537(jm2c00120, Compound 34)
Affinity DataIC50:  80nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533518(jm2c00120, Compound 17)
Affinity DataIC50:  80nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152587(2-(1-(Benzofuran-2-yl)ethylidene)-N-phenylhydrazin...)
Affinity DataIC50:  89nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533534(jm2c00120, Compound 31)
Affinity DataIC50:  100nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152600(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-methoxyphen...)
Affinity DataIC50:  102nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533536(jm2c00120, Compound 33)
Affinity DataIC50:  114nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533515(jm2c00120, Compound 15)
Affinity DataIC50:  146nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152591(2-(1-(Benzofuran-2-yl)ethylidene)-N-(4-fluoropheny...)
Affinity DataIC50:  177nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152598(2-(1-(Benzofuran-2-yl)ethylidene)-N-(4-nitrophenyl...)
Affinity DataIC50:  181nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533514(jm2c00120, Compound 14)
Affinity DataIC50:  244nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50:  278nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM57806(1-[1-(1-benzofuran-2-yl)ethylideneamino]-3-(3-meth...)
Affinity DataIC50:  283nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152602(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2-methylpheny...)
Affinity DataIC50:  314nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152593(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2-fluoropheny...)
Affinity DataIC50:  321nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533513(jm2c00120, Compound 13)
Affinity DataIC50:  342nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533529(jm2c00120, Compound 29)
Affinity DataIC50:  344nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50:  360nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152594(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2,4-difluorop...)
Affinity DataIC50:  387nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533531(jm2c00120, Compound 30)
Affinity DataIC50:  442nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533528(jm2c00120, Compound 28)
Affinity DataIC50:  482nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533524(jm2c00120, Compound 23)
Affinity DataIC50:  514nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533516(jm2c00120, Compound 16)
Affinity DataIC50:  516nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Pig)
Minia University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  520nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as decrease in fluorescence intensity measured every 60 sec for 90 mins in presence of GT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152596(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2-bromophenyl...)
Affinity DataIC50:  564nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152589(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2,4-dichlorop...)
Affinity DataIC50:  592nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152603(N-Allyl-2-(1-(benzofuran-2-yl)ethylidene)hydrazine...)
Affinity DataIC50:  694nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Pig)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504214(CHEMBL4530425)
Affinity DataIC50:  700nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as decrease in fluorescence intensity measured every 60 sec for 90 mins in presence of GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Pig)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504216(CHEMBL4472670)
Affinity DataIC50:  760nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as decrease in fluorescence intensity measured every 60 sec for 90 mins in presence of GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533522(jm2c00120, Compound 21)
Affinity DataIC50:  899nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533525(jm2c00120, Compound 24)
Affinity DataIC50:  960nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533523(jm2c00120, Compound 22)
Affinity DataIC50:  1.01E+3nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTubulin beta chain(Pig)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504215(CHEMBL4463939)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of porcine brain tubulin polymerization assessed as decrease in fluorescence intensity measured every 60 sec for 90 mins in presence of GT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152588(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-chloropheny...)
Affinity DataIC50:  1.13E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152592(2-(1-(Benzofuran-2-yl)ethylidene)-N-(3-fluoropheny...)
Affinity DataIC50:  1.15E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Montpellier

LigandPNGBDBM533508(jm2c00120, Compound 7)
Affinity DataIC50:  1.40E+3nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533504(jm2c00120, Compound 5)
Affinity DataIC50:  1.44E+3nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM152590(2-(1-(Benzofuran-2-yl)ethylidene)-N-(2,5-dichlorop...)
Affinity DataIC50:  2.01E+3nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 無 of enzyme (5 U/mL) and 10 無 of each test compound in the series (3a-3s) in 40 無 b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Minia University

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Montpellier

LigandPNGBDBM533508(jm2c00120, Compound 7)
Affinity DataIC50:  2.07E+3nMAssay Description:The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
Minia University

Curated by ChEMBL
LigandPNGBDBM50504214(CHEMBL4530425)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of [3H] colchicine binding to bovine brain tubulin incubated for 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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