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Found 46 with Last Name = 'iwayama' and Initial = 's'
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101813(CHEBI:31399 | Cilnidipine)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211650(3-(4-(4-((1-(2-chlorocyclopent-1-enyl)ethoxy)carbo...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50475659(CHEMBL508181)
Affinity DataIC50:  46nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211649(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  48nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211647(3-(4-(4-((1-(2-chlorocyclohex-1-enyl)ethoxy)carbon...)
Affinity DataIC50:  56nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211646(5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  72nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211655(4-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  73nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211645(2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  74nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211651(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  81nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211648(2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211653(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211654(5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  120nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211648(2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211650(3-(4-(4-((1-(2-chlorocyclopent-1-enyl)ethoxy)carbo...)
Affinity DataIC50:  130nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211655(4-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  140nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50170859(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211647(3-(4-(4-((1-(2-chlorocyclohex-1-enyl)ethoxy)carbon...)
Affinity DataIC50:  170nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211646(5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211649(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  220nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211651(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  260nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211653(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  280nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211654(5-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  370nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50052428(2-(2,6-Dioxo-piperidin-3-yl)-4,5,6,7-tetrafluoro-i...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against TNF-alpha productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211645(2-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)isoxaz...)
Affinity DataIC50:  430nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50170859(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Affinity DataIC50:  510nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383776(CHEMBL2030594)
Affinity DataIC50:  520nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383765(CHEMBL2030603)
Affinity DataIC50:  580nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383765(CHEMBL2030603)
Affinity DataIC50:  580nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383769(CHEMBL2030600)
Affinity DataIC50:  750nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383765(CHEMBL2030603)
Affinity DataIC50:  840nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383775(CHEMBL2030593)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383774(CHEMBL2030592)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383766(CHEMBL2030597)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383773(CHEMBL2030591)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383778(CHEMBL2030596)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383768(CHEMBL2030599)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383770(CHEMBL2030601)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383771(CHEMBL2030602)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383777(CHEMBL2030595)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383767(CHEMBL2030598)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Rattus norvegicus)
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211652(3-{2'-[1-(2-chloro-phenyl)-ethoxycarbonylamino]-bi...)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at LPA1 receptor in rat hepatic stellate cells assessed as inhibition of lysophosphatidic acid-induced intracellular calcium infl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
Ajinomoto

Curated by ChEMBL
LigandPNGBDBM50211652(3-{2'-[1-(2-chloro-phenyl)-ethoxycarbonylamino]-bi...)
Affinity DataIC50: >4.00E+4nMAssay Description:Antagonist activity at human recombinant LPA1 receptor expressed in CHOK1 cells assessed as inhibition of lysophosphatidic acid-induced intracellular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed