Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 0.140nMAssay Description:Affinity towards cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:In vitro binding affinity to human Dopamine receptor D4More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Affinity towards cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(RAT)
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 0.870nMAssay Description:In vitro affinity for cloned rat metabotropic glutamate 1 receptors stably expressed on CHO cells determined using [3H]-R214127 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I]sauvagine from CRF1 receptor expressed in human IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.04nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.07nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.12nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.19nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.46nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:In vitro binding affinity towards cloned human 5-HT1B receptor using [3H]5-carboximidotryptamine as radioligandMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 1.83nMAssay Description:In vitro displacement of [3H]-paroxetine from human serotonin transporter expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Affinity towards 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [125I]sauvagine from CRF1 receptor expressed in human IMR32 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-PYY from human recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Columbia University College Of Physicians And Surgeons
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125]sauvagin from rat recombinant NPY Y1 receptor overexpressed in membrane of Sf9 cellsMore data for this Ligand-Target Pair