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Found 531 with Last Name = 'baguley' and Initial = 'td'
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103445(CHEMBL3398243)
Affinity DataKi:  109nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50067512(CHEMBL3401893)
Affinity DataKi:  115nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103444(CHEMBL3398244)
Affinity DataKi:  116nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103448(CHEMBL3398247)
Affinity DataKi:  123nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103447(CHEMBL3398250)
Affinity DataKi:  124nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103450(CHEMBL3398249)
Affinity DataKi:  175nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103443(CHEMBL3398245)
Affinity DataKi:  183nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103446(CHEMBL3398251)
Affinity DataKi:  210nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50103449(CHEMBL3398248)
Affinity DataKi:  230nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50067504(CHEMBL3398246)
Affinity DataKi:  235nMAssay Description:Inhibition of STEP (unknown origin) in absence of GSH by p-nitrophenyl phosphate hydrolysis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312266((4-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)pheny...)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312260((4-(3,5-bis(trifluoromethyl)phenylcarbamoyl)phenyl...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312259((4-(4-bromo-3-(trifluoromethyl)phenylcarbamoyl)phe...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312258((4-(4-chloro-3-(trifluoromethyl)phenylcarbamoyl)ph...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441296(CHEMBL2431665 | CHEMBL2431667)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441302(CHEMBL2431688)
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441297(CHEMBL2431664 | CHEMBL2431666)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441304(CHEMBL2431686)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312256((4-(4-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312252(CHEMBL1080488 | difluoro(4-(3-(trifluoromethyl)phe...)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312257(CHEMBL1080667 | difluoro(4-(4-fluoro-3-(trifluorom...)
Affinity DataKi:  1.14E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50312261((4-(4-bromo-3,5-bis(trifluoromethyl)phenylcarbamoy...)
Affinity DataKi:  1.48E+4nMAssay Description:Inhibition of human HCPTPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441303(CHEMBL2431687)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312255((4-(4-chlorophenylcarbamoyl)phenyl)difluoromethylp...)
Affinity DataKi:  1.68E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312251((4-(3-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312254(CHEMBL1080494 | difluoro(4-(4-(trifluoromethyl)phe...)
Affinity DataKi:  1.85E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441305(CHEMBL2431685)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312253(CHEMBL1075857 | difluoro(4-(4-fluorophenylcarbamoy...)
Affinity DataKi:  2.27E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312244(CHEMBL1080018 | difluoro(4-(phenylcarbamoyl)phenyl...)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441322(CHEMBL2431707)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312243(CHEMBL1080017 | difluoro(4-(thiazol-2-ylcarbamoyl)...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312250((4-(3-chlorophenylcarbamoyl)phenyl)difluoromethylp...)
Affinity DataKi:  3.49E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441306(CHEMBL2431684)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441320(CHEMBL2431670)
Affinity DataKi:  3.60E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312249(CHEMBL1080201 | difluoro(4-(3-fluorophenylcarbamoy...)
Affinity DataKi:  4.18E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312242((4-(benzylcarbamoyl)phenyl)difluoromethylphosphoni...)
Affinity DataKi:  4.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312248((4-(2-bromophenylcarbamoyl)phenyl)difluoromethylph...)
Affinity DataKi:  4.46E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441323(CHEMBL2431706)
Affinity DataKi:  4.50E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312241(CHEMBL1081937 | difluoro(4-(2,2,2-trifluoroethylca...)
Affinity DataKi:  4.97E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312247(CHEMBL1075838 | difluoro(4-(2-(trifluoromethyl)phe...)
Affinity DataKi:  5.48E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312240(CHEMBL1081936 | difluoro(4-(phenethylcarbamoyl)phe...)
Affinity DataKi:  6.16E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441321(CHEMBL2431669)
Affinity DataKi:  6.20E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441324(CHEMBL2431705)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312231((4-benzamidophenyl)difluoromethylphosphonic acid |...)
Affinity DataKi:  6.55E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312246((4-(2-chlorophenylcarbamoyl)phenyl)difluoromethylp...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441327(CHEMBL2431702)
Affinity DataKi:  6.90E+4nMAssay Description:Inhibition of human STEP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50441298(CHEMBL2431708)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of human TC-PTP using pNPP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
University Of California

Curated by ChEMBL
LigandPNGBDBM50312239((4-(cyclopentylcarbamoyl)phenyl)difluoromethylphos...)
Affinity DataKi:  7.24E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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