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Found 68 with Last Name = 'barba' and Initial = 'o'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362677(CHEMBL1939618)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362678(CHEMBL1939480)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362683(CHEMBL1939476)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  14nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362685(CHEMBL1939475)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27577(5-[(3-ethyl-5-fluoro-1H-indazol-4-yl)oxy]benzene-1...)
Affinity DataIC50:  25nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362675(CHEMBL1939620)
Affinity DataIC50:  28nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362676(CHEMBL1939621)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27577(5-[(3-ethyl-5-fluoro-1H-indazol-4-yl)oxy]benzene-1...)
Affinity DataIC50:  32nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362667(CHEMBL1939631)
Affinity DataIC50:  37nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362680(CHEMBL1939478)
Affinity DataIC50:  38nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362672(CHEMBL1939622)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  40nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27579(AG 1549 | CPV | Capravirine | {5-[(3,5-dichlorophe...)
Affinity DataIC50:  47nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362667(CHEMBL1939631)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27576(5-[(5-fluoro-3-methyl-1H-indazol-4-yl)oxy]benzene-...)
Affinity DataIC50:  50nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362673(CHEMBL1939624)
Affinity DataIC50:  53nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27579(AG 1549 | CPV | Capravirine | {5-[(3,5-dichlorophe...)
Affinity DataIC50:  61nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27579(AG 1549 | CPV | Capravirine | {5-[(3,5-dichlorophe...)
Affinity DataIC50:  68nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27578(5-{[7-(hydroxymethyl)-3-methyl-1H-indazol-4-yl]oxy...)
Affinity DataIC50:  71nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362666(CHEMBL1939628)
Affinity DataIC50:  97nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362665(CHEMBL1939632)
Affinity DataIC50:  102nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362665(CHEMBL1939632)
Affinity DataIC50:  102nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362671(CHEMBL1939623)
Affinity DataIC50:  110nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27572(5-[(3-ethyl-1H-indazol-4-yl)oxy]benzene-1,3-dicarb...)
Affinity DataIC50:  112nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362669(CHEMBL1939625)
Affinity DataIC50:  115nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362670(CHEMBL1939627)
Affinity DataIC50:  117nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362666(CHEMBL1939628)
Affinity DataIC50:  125nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362687(CHEMBL1939474)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362679(CHEMBL1939617)
Affinity DataIC50:  144nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27576(5-[(5-fluoro-3-methyl-1H-indazol-4-yl)oxy]benzene-...)
Affinity DataIC50:  145nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362674(CHEMBL1939619)
Affinity DataIC50:  167nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27577(5-[(3-ethyl-5-fluoro-1H-indazol-4-yl)oxy]benzene-1...)
Affinity DataIC50:  183nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362671(CHEMBL1939623)
Affinity DataIC50:  220nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362684(CHEMBL1939477)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27571(5-[(3-methyl-1H-indazol-4-yl)oxy]benzene-1,3-dicar...)
Affinity DataIC50:  332nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362682(CHEMBL1939473)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM2483((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...)
Affinity DataIC50:  364nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362668(CHEMBL1939626)
Affinity DataIC50:  373nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27576(5-[(5-fluoro-3-methyl-1H-indazol-4-yl)oxy]benzene-...)
Affinity DataIC50:  384nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27575(5-[(5-chloro-3-methyl-1H-indazol-4-yl)oxy]benzene-...)
Affinity DataIC50:  399nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362669(CHEMBL1939625)
Affinity DataIC50:  433nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362676(CHEMBL1939621)
Affinity DataIC50:  440nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362688(CHEMBL1939630)
Affinity DataIC50:  520nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362668(CHEMBL1939626)
Affinity DataIC50:  709nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362686(CHEMBL1939479)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27578(5-{[7-(hydroxymethyl)-3-methyl-1H-indazol-4-yl]oxy...)
Affinity DataIC50:  1.27E+3nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27574(5-{[3-(methoxymethyl)-1H-indazol-4-yl]oxy}benzene-...)
Affinity DataIC50:  1.67E+3nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Mus musculus (mouse))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362677(CHEMBL1939618)
Affinity DataIC50:  1.96E+3nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis n mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Prosidion

Curated by ChEMBL
LigandPNGBDBM50362681(CHEMBL1305904)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of human recombinant N-terminus FLAG-tagged DGAT1 expressed in baculovirus infected insect Sf9 cells assessed as triglyceride synthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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