TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.0470nMAssay Description:Compound was evaluated for the inhibition of human Coagulation factor XaMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [125I]sauvagine from human CRF1 receptor expressed in IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Antagonist activity at rat CB1 receptor in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nMAssay Description:Antagonist activity at rat CB1 receptor in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of factor 10a by amidolytic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of factor 10a by amidolytic assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -51.7kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Antagonist activity at rat CB1 receptor in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [125I]sauvagine from CRF1 receptor expressed in human IMR32 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Compound was evaluated for binding affinity against human Dopamine receptor D3 transfected in CHO cell membranes to stimulate [3H]-thymidine uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Antagonist activity at human CRF-1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.1kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity at dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.1kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 0.910nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 endogenously expressed in IMR-32 human neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Coagulation factor XaMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of Coagulation factor XaMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity towards Dopamine type 2 receptor was determined by displacement assays using [3H]-YM 09151 as the competitive ligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -50.6kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -50.2kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-sauvagine from human CRF-1 receptor expressed in human IMR-32 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Compound was evaluated for binding affinity against human Dopamine receptor D3 transfected in CHO cell membranes to stimulate [3H]-thymidine uptakeMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity at dopamine receptor D3More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity at dopamine receptor D3More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity against serine protease factor Xa (fXa)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair