Affinity DataKi: 0.0400nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 58.8nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.98E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 93nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta 5 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta 5 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta 5 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of trypsin-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of trypsin-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta 5 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of trypsin-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta 5 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 656nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 794nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of trypsin-like activity of proteasome in human NCI-H929 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta 5 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome in human RPMI-8226 cells after 6 hrs by proteasomeGlo assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 1.45E+3nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Leiden Institute Of Chemistry And Netherlands Proteomics Centre
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of trypsin-like activity of proteasome beta 2 subunit in HEK-293T cell lysates using BODIPY-BODIPY-TMR-epoxomicin as probe after 1 hr by S...More data for this Ligand-Target Pair