TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 430nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 540nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectrophot...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 3.90E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Inhibition of TC-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectrop...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 5.60E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectroph...More data for this Ligand-Target Pair
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of LMW-PTP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectro...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 6.80E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 9.60E+3nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Inhibition of STEP (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.140nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.550nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.850nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 0.850nMAssay Description:Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant PDE10A expressed in baculovirus-SF21 cell system assessed as hydrolysis of [3H]cAMP after 1 hr by liquid scintillatio...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.48nMAssay Description:Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.48nMAssay Description:Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.53nMAssay Description:Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.65nMAssay Description:Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysisMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair