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Found 32 with Last Name = 'buss' and Initial = 'ad'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250840(5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dim...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250841(CHEMBL463250 | N-3'-ethylaplysinopsin)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250840(5-(6-Bromo-1H-indol-3-ylmethylene)-2-imino-1,3-dim...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250839(6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250841(CHEMBL463250 | N-3'-ethylaplysinopsin)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [3H]mesulergine form human cloned 5HT2C receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250839(6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]methylspiperone form human cloned 5HT2A receptor expressed in african green monkey COS7 cells by scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Molecular And Cell Biology

Curated by ChEMBL
LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  3.00E+3nMAssay Description:inhibition of Mycobacterium tuberculosis InhA after 20 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260106(CHEMBL519317 | Variecolin)
Affinity DataIC50:  9.00E+3nMAssay Description:Displacement of human [125I]MIP-1alpha from human CCR5 overexpressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293172((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50242234(CHEMBL512035 | fuscin)
Affinity DataIC50:  2.10E+4nMAssay Description:Displacement of [125I]human-MIP1alpha from human CCR5 receptor expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50260107(CHEMBL484427 | Variecolol)
Affinity DataIC50:  3.20E+4nMAssay Description:Displacement of human [125I]MIP-1alpha from human CCR5 overexpressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250839(6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
The University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50250839(6-bromo-2'-de-N-methylaplysinopsin | CHEMBL2058413...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Institute Of Molecular And Cell Biology

Curated by ChEMBL
LigandPNGBDBM50242321(Agonodepside A | CHEMBL454588)
Affinity DataIC50:  7.50E+4nMAssay Description:inhibition of Mycobacterium tuberculosis InhA after 20 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50242056(CHEMBL469856 | fuscinarin)
Affinity DataIC50:  8.00E+4nMAssay Description:Displacement of [125I]human-MIP1alpha from human CCR5 receptor expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50242233(10-methoxydihydrofuscin | CHEMBL459020)
Affinity DataIC50:  1.54E+5nMAssay Description:Displacement of [125I]human-MIP1alpha from human CCR5 receptor expressed in CHO cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293170((1R,12S,16S,19R,20R,21S,22R)-4,8,21-Trihydroxy-10-...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKd:  3.38E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50269239(CHEMBL501713 | sundaicumone A)
Affinity DataEC50:  1.73E+5nMAssay Description:Activity at glucocorticoid receptor in human A549 cells assessed as effect on GRE promoter response by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Luciola lateralis)
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357676(CHEMBL1914948)
Affinity DataEC50:  730nMAssay Description:Inhibition of firefly luciferase by ATPlite assay in absence of AMPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataEC50:  1nMAssay Description:Activity at glucocorticoid receptor in human A549 cells assessed as effect on GRE promoter response by luciferase reporter assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50269240(CHEMBL524715 | sundaicumone B)
Affinity DataEC50:  7.50E+4nMAssay Description:Activity at glucocorticoid receptor in human A549 cells assessed as effect on GRE promoter response by luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataKd:  3.99E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataKd:  1.83E+6nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)
Affinity DataKd:  1.71E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293171((1R,2S,4S,6E,8S,11R,12R,13S,14R,15R,22R)-13-hydrox...)
Affinity DataKd:  3.77E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293170((1R,12S,16S,19R,20R,21S,22R)-4,8,21-Trihydroxy-10-...)
Affinity DataKd:  1.08E+7nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293169(CHEMBL523927 | kendomycin)
Affinity DataKd:  5.28E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed