Affinity DataKi: 0.0600nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 23.4nMAssay Description:Binding affinity to human 5HT3A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 440nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 470nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 580nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 710nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
Affinity DataKi: 5.79E+4nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 9.91E+4nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
Affinity DataKi: 1.35E+5nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 1More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Increased REV-ERB-beta LBD dependent repressor activity in HEK293 cell reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 620nMAssay Description:REV-ERB-alpha mediated transcriptional suppression at Bmal1 promoter in HEK293 cell reporter assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Increased REV-ERB-alpha LBD dependent repressor activity in HEK293 cell reporter assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:REV-ERB-alpha mediated transcriptional suppression at Bmal1 promoter in HEK293 cell reporter assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Increased REV-ERB-alpha LBD dependent repressor activity in HEK293 cell reporter assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Increased REV-ERB-beta LBD dependent repressor activity in HEK293 cell reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group D member 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataKd: 800nMAssay Description:Dissociation constant for binding to REV-ERB-alpha by circular dichroismMore data for this Ligand-Target Pair
Affinity DataEC50: 12.6nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
Affinity DataEC50: 14.5nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
Affinity DataEC50: 5.40nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair
Affinity DataEC50: 178nMAssay Description:Partial agonist activity at human 5HT3A receptor expressed in HEK293 cells assessed as effect on serotonin-induced responseMore data for this Ligand-Target Pair