Affinity DataKi: 0.800nM IC50: 4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of biotinylated human FXIa assessed as inhibition of p-nitroaniline release using Pyr-Pro-Arg-pNA as substrate measured for 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nM IC50: 5nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of biotinylated human FXIa assessed as inhibition of p-nitroaniline release using Pyr-Pro-Arg-pNA as substrate measured for 20 minsMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of biotinylated human FXIa assessed as inhibition of p-nitroaniline release using Pyr-Pro-Arg-pNA as substrate measured for 20 minsMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Inhibition of biotinylated human FXIa assessed as inhibition of p-nitroaniline release using Pyr-Pro-Arg-pNA as substrate measured for 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 3nM IC50: 9nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Inhibition of biotinylated human FXIa assessed as inhibition of p-nitroaniline release using Pyr-Pro-Arg-pNA as substrate measured for 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 11nM IC50: 30nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:The compound was evaluated for the inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 17nM IC50: 42nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 23nM IC50: 83nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Inhibition of biotinylated human FXIa assessed as inhibition of p-nitroaniline release using Pyr-Pro-Arg-pNA as substrate measured for 20 minsMore data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:The compound was evaluated for the inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:The compound was evaluated for the inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:In vitro inhibtion of human thrombin.More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Inhibitory activity against bovine thrombinMore data for this Ligand-Target Pair