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Found 48 with Last Name = 'chung' and Initial = 'hy'
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataKi:  374nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50485276(CHEMBL233375)
Affinity DataKi:  413nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataKi:  567nMAssay Description:Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50339940(4-(Benzo[d]thiazol-2-yl)benzene-1,3-diol | CHEMBL1...)
Affinity DataKi:  673nMAssay Description:Inhibition of mushroom tyrosinase at 1.25 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataKi:  840nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 20 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50485276(CHEMBL233375)
Affinity DataKi:  1.38E+3nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 20 uM by Line-Weaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of mushroom tyrosinase at 20 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50339940(4-(Benzo[d]thiazol-2-yl)benzene-1,3-diol | CHEMBL1...)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of mushroom tyrosinase at 20 uM by Lineweaver-burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50339940(4-(Benzo[d]thiazol-2-yl)benzene-1,3-diol | CHEMBL1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50197244(4-(6-hydroxynaphthalen-2-yl)benzene-1,3-diol | CHE...)
Affinity DataIC50:  34nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50197242(7-(3,5-dihydroxyphenyl)naphthalene-1,3-diol | CHEM...)
Affinity DataIC50:  490nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50492368(CHEMBL2401797)
Affinity DataIC50:  500nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as amount of dopachrome produced after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM33932(4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50197243(5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol | 5-(6...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as inhibition of oxidation L-DOPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50197243(5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol | 5-(6...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50197243(5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol | 5-(6...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: >3.30E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  4.12E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  6.12E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50168371(6-(3-Hydroxy-phenyl)-naphthalen-2-ol | 6-(3-hydrox...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60918(5-Amino-2-hydroxy-benzoic acid | MESALAMINE | MLS0...)
Affinity DataIC50:  7.53E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50528483(CHEMBL4448450)
Affinity DataIC50:  7.59E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60918(5-Amino-2-hydroxy-benzoic acid | MESALAMINE | MLS0...)
Affinity DataIC50:  7.73E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataIC50:  8.91E+3nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50485276(CHEMBL233375)
Affinity DataIC50:  9.87E+3nMAssay Description:Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of recombinant human COX2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM60579((5Z)-5-(4-hydroxybenzylidene)thiazolidine-2,4-quin...)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50186767(5-(6-Hydroxy-naphthalen-2-yl)-benzene-1,3-diol | 5...)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  1.88E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  2.47E+4nMAssay Description:Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  2.66E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50486146(Azo-Resveratrol | CHEMBL2208146)
Affinity DataIC50:  3.63E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  3.82E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  3.82E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50528483(CHEMBL4448450)
Affinity DataIC50:  3.92E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50486145(CHEMBL2208145)
Affinity DataIC50:  5.02E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as amount of dopachrome produced after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  5.56E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  5.56E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Pusan National University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed