Affinity DataIC50: 1.90nMAssay Description:Inhibition of aromatase in human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hr by liquid scintillation counting met...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluorime...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluorime...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 253nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 276nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 428nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 446nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluorime...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 534nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 681nMAssay Description:Inhibition of recombinant N-terminal His-tagged human iNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins follo...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human aromatase preincubated for 10 mins followed by substrate and beta-NADP+ addition and measured for 60 mins by fluorime...More data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition of human CYP19A measured every 1 min for 60 mins by flourimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Inhibition of human CYP19A measured every 1 min for 60 mins by flourimetric assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity using 7-methoxy-4-trifluoromethyl coumarin as a substrate by fluorimetr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity using 7-methoxy-4-trifluoromethyl coumarin as a substrate by fluorimetr...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human aromatase in T47D measured after 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant human nNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins followed by NADPH addition ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant human nNOS expressed in Escherichia coli using L-arginine as substrate preincubated for 15 mins followed by NADPH addition ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant rat nNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity using 7-methoxy-4-trifluoromethyl coumarin as a substrate by fluorimetr...More data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity using 7-methoxy-4-trifluoromethyl coumarin as a substrate by fluorimetr...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human eNOS using L-argininge as substrate preincubated for 15 mins followed by NADPH addition and measured after 20 mins by OPA/NAC rea...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant rat nNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human aromatase using dibenzylfluorescein as a substrate preincubated with NADPH regenerating system for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human aromatase using dibenzylfluorescein as a substrate preincubated with NADPH regenerating system for 10 mins followed by substrate ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 2.11E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 2.65E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
University "G. D'Annunzio" Of Chieti-Pescara
Curated by ChEMBL
Affinity DataIC50: 3.04E+5nMAssay Description:Inhibition of human eNOS using L-argininge as substrate preincubated for 15 mins followed by NADPH addition and measured after 20 mins by OPA/NAC rea...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 3.31E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
University Of Chieti "G. D'Annunzio
Curated by ChEMBL
Affinity DataIC50: 3.84E+5nMAssay Description:Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...More data for this Ligand-Target Pair