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Found 175 with Last Name = 'hayes' and Initial = 'r'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048302(4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmeth...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048302(4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmeth...)
Affinity DataKi:  0.520nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048300(4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-te...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048300(4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-te...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048302(4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmeth...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048301(4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  8.40nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048300(4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-te...)
Affinity DataKi:  10.3nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  16.6nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  25.5nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048301(4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...)
Affinity DataKi:  56.7nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048302(4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmeth...)
Affinity DataKi:  61.4nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D4.2 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048300(4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-te...)
Affinity DataKi:  68nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D4.2 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  90.9nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D4.2 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048301(4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...)
Affinity DataKi:  94nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048301(4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D4.2 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50041945(1N-ethyl-2-benzylcarboxamido-2-[4-{2-[2-benzylcarb...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50041946(1N-(2,2,2-trifluoroethyl)-2-benzylcarboxamido-2-[4...)
Affinity DataIC50:  4.40nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50041944(1N-benzyl-2-[4-{3-[2-benzylcarbamoyl(benzylcarboxa...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50041949(4N-{2-[5-ethylcarbamoyl(5-methyl-3-phenyl-4-isoxaz...)
Affinity DataIC50:  5.40nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50241203(CHEMBL414357 | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGS...)
Affinity DataIC50:  6nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557258(CHEMBL4796216)
Affinity DataIC50:  7.10nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50041948(4N-{2-[5-ethylcarbamoyl(2-phenylphenylcarboxamido)...)
Affinity DataIC50:  9.90nMAssay Description:Inhibitory activity against HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataIC50:  10nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50466532(CHEMBL4281479)
Affinity DataIC50:  12nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50197025(CHEMBL439904 | PYY(3-36))
Affinity DataIC50:  16nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557262(CHEMBL4759334)
Affinity DataIC50:  18nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391318(CHEMBL161422)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557263(CHEMBL4752195)
Affinity DataIC50:  25nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557264(CHEMBL4751466)
Affinity DataIC50:  27nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataIC50:  28nMAssay Description:Displacement of GLP-1-red from human GLP-1R expressed in CHO-K1 cells by fluorescent competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391324(CHEMBL348790 | GR-85305)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataIC50:  32nMAssay Description:In vitro TXA2 synthase antagonism through inhibition of collagen induced thromboxane-A2 production in human citrated whole bloodChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataIC50:  32nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50003795(5-[1-Pyridin-3-yl-1-(3-trifluoromethyl-phenyl)-met...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticleDrugBank

TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391322(CHEMBL351657)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391317(CHEMBL162641 | GR-108774)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391321(CHEMBL162879)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557261(CHEMBL4749279)
Affinity DataIC50:  41nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557259(CHEMBL4748874)
Affinity DataIC50:  47nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391316(CHEMBL422017)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391319(CHEMBL164109)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391325(CHEMBL159447)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557260(CHEMBL4741000)
Affinity DataIC50:  61nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391327(CHEMBL159936)
Affinity DataIC50:  63nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391323(CHEMBL347812)
Affinity DataIC50:  79nMAssay Description:In vitro inhibition of collagen-induced thromboxane A2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Syracuse University

Curated by ChEMBL
LigandPNGBDBM50557262(CHEMBL4759334)
Affinity DataIC50:  82nMAssay Description:Agonist activity at human NPY1R expressed in HEK293 cells assessed as inhibition of adenosine-induced stimulation of cAMP accumulation by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391309(CHEMBL159517 | GR-83783)
Affinity DataIC50:  100nMAssay Description:In vitro TXA2 synthase antagonism through inhibition of collagen induced thromboxane-A2 production in human citrated whole bloodChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391303(CHEMBL158576)
Affinity DataIC50:  100nMAssay Description:In vitro TXA2 synthase antagonism through inhibition of collagen induced thromboxane-A2 production in human citrated whole bloodChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391302(CHEMBL349625)
Affinity DataIC50:  100nMAssay Description:In vitro TXA2 synthase antagonism through inhibition of collagen induced thromboxane-A2 production in human citrated whole bloodChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
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