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Found 31 with Last Name = 'kain' and Initial = 'kc'
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  190nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341908(((2S,3S,4R,5R)-5-(5-azido-2,4-dioxo-3,4-dihydropyr...)
Affinity DataKi:  630nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21338(6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  840nM ΔG°:  -38.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM21338(6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  2.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50398698(CHEMBL2178721)
Affinity DataKi:  1.11E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.24E+4nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM50398698(CHEMBL2178721)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute

LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | C6-Uridine De...)
Affinity DataKi:  2.24E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.60E+4nM ΔG°:  -27.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398698(CHEMBL2178721)
Affinity DataKi:  2.83E+4nMAssay Description:Inhibition of human ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.90E+4nM ΔG°:  -28.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | C6-Uridine De...)
Affinity DataKi:  3.41E+4nM ΔG°:  -26.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341905(CHEMBL1765124 | ammonium 6-Cyano-2'-deoxy-2'-fluor...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  6.20E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | C6-Uridine De...)
Affinity DataKi:  1.34E+5nM ΔG°:  -24.3kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of human ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  3.30E+5nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341907(CHEMBL1765122 | ammonium 5-Cyano-2'-deoxy-2'-fluor...)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50341907(CHEMBL1765122 | ammonium 5-Cyano-2'-deoxy-2'-fluor...)
Affinity DataKi:  7.59E+5nMAssay Description:Inhibition of human 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM50398697(CHEMBL2178722)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341909(CHEMBL1765126 | ammonium 6-Azido-2'-deoxy-2'-fluor...)
Affinity DataKi:  1.20E+6nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50310540(((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)...)
Affinity DataKi:  1.20E+6nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50310540(((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)...)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition of human ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50341905(CHEMBL1765124 | ammonium 6-Cyano-2'-deoxy-2'-fluor...)
Affinity DataKi: >2.00E+6nMAssay Description:Inhibition of human 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341906(Ammonium 6-Amido-2'-deoxy-2'-fluoro-beta-D-uridine...)
Affinity DataKi:  3.32E+6nMAssay Description:Inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine 5'-monophosphate synthase(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50341906(Ammonium 6-Amido-2'-deoxy-2'-fluoro-beta-D-uridine...)
Affinity DataKi: >4.00E+6nMAssay Description:Inhibition of human 5'-monophosphate decarboxylase by VP-ITC microcalorimeterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
Toronto General Research Institute

LigandPNGBDBM50310540(((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine 5'-phosphate decarboxylase(Methanobacterium thermoautotrophicum)
Toronto General Research Institute

LigandPNGBDBM50341905(CHEMBL1765124 | ammonium 6-Cyano-2'-deoxy-2'-fluor...)
Affinity DataKi:  3.00E+7nMAssay Description:Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed