Affinity DataIC50: 0.800nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC3 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC4 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC2 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of COX1 assessed as inhibition of arachidonic acid conversion to prostaglandin-E2 releaseMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human COX1-mediated conversion of arachidonic acid to prostaglandin-E2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of cyclooxygenase 1More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC9 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC3 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC9 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC7 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC3 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC4 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC4 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HDAC2 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of HDAC2 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of HDAC7 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of HDAC3 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of HDAC9 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of HDAC2 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of HDAC7 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
Affinity DataIC50: 3.07E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
Affinity DataIC50: 3.08E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
Affinity DataIC50: 4.87E+4nMAssay Description:Inhibition of HDAC4 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40E+4nMpH: 5.0 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 365 nm, emission 4...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair