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Found 368 with Last Name = 'lydon' and Initial = 'nb'
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287090(4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287090(4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  38nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287091(CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...)
Affinity DataIC50:  50nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
Affinity DataIC50:  50nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287091(CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...)
Affinity DataIC50:  50nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240407(CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...)
Affinity DataIC50:  100nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240407(CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...)
Affinity DataIC50:  100nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287094(CHEMBL278630 | N-[4-Chloro-3-(4-pyridin-3-yl-pyrim...)
Affinity DataIC50:  150nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290417(2-Amino-pyrimidine, 19 | CHEMBL418270 | N-[3-(4-Py...)
Affinity DataIC50:  150nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  180nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287091(CHEMBL20252 | Naphthalene-2-carboxylic acid [4-met...)
Affinity DataIC50:  200nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290412(4-Fluoro-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290431(CHEMBL56669 | Hexanoic acid [3-(4-pyridin-3-yl-pyr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175491(4-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  200nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290413(CHEMBL55379 | [4-(1H-Indol-3-yl)-pyrimidin-2-yl]-[...)
Affinity DataIC50:  290nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287096(2-Methoxy-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of tyrosine kinase(PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290427(CHEMBL56359 | Thiophene-2-carboxylic acid [3-(4-py...)
Affinity DataIC50:  300nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287096(2-Methoxy-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290420((4-Pyridin-4-yl-pyrimidin-2-yl)-[3-(1,1,2,2-tetraf...)
Affinity DataIC50:  300nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290429(2-Methoxy-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino...)
Affinity DataIC50:  320nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290411(4-Cyano-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-...)
Affinity DataIC50:  350nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  350nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290413(CHEMBL55379 | [4-(1H-Indol-3-yl)-pyrimidin-2-yl]-[...)
Affinity DataIC50:  370nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50240407(CHEMBL20926 | N-(4-methyl-3-(4-(pyridin-3-yl)pyrim...)
Affinity DataIC50:  400nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50175493(CHEMBL277931 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290415(CHEMBL59099 | N-(3-Amino-propyl)-3-(4-pyridin-3-yl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290419(CHEMBL58142 | Cyclohexanecarboxylic acid [3-(4-pyr...)
Affinity DataIC50:  450nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  500nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50:  500nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  530nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290431(CHEMBL56669 | Hexanoic acid [3-(4-pyridin-3-yl-pyr...)
Affinity DataIC50:  600nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045408(CHEMBL57443 | N-(4-Pyridin-4-yl-pyrimidin-2-yl)-be...)
Affinity DataIC50:  600nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045528(CHEMBL57553 | N-(4-Pyridin-3-yl-pyrimidin-2-yl)-be...)
Affinity DataIC50:  700nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290423((3-Nitro-phenyl)-(4-pyridin-3-yl-pyrimidin-2-yl)-a...)
Affinity DataIC50:  790nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287096(2-Methoxy-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290419(CHEMBL58142 | Cyclohexanecarboxylic acid [3-(4-pyr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50287090(4-Chloro-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2...)
Affinity DataIC50:  800nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290425(CHEMBL57581 | [4-(4-Chloro-phenyl)-pyrimidin-2-yl]...)
Affinity DataIC50:  850nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045526(CHEMBL58436 | [3-(2-Imidazol-1-yl-ethoxy)-phenyl]-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.00E+3nMAssay Description:Determination of EGF receptor kinase activity was performed as described using A431 membranes as the enzyme source and agiotensin II as substrate.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290429(2-Methoxy-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM92633(Thiazolidine-dione, 2)
Affinity DataIC50:  1.00E+3nMAssay Description:Determination of EGF receptor kinase activity was performed as described using A431 membranes as the enzyme source and agiotensin II as substrate.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50045481((3-Imidazol-1-yl-phenyl)-(4-pyridin-3-yl-pyrimidin...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
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