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Found 61 with Last Name = 'marriott' and Initial = 'jh'
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50403879(CHEMBL320217)
Affinity DataKi:  0.170nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088159(4-[3-Carboxy-1-(1H-tetrazol-5-yl)-propylcarbamoyl]...)
Affinity DataKi:  0.200nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088159(4-[3-Carboxy-1-(1H-tetrazol-5-yl)-propylcarbamoyl]...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408128(CHEMBL30179)
Affinity DataKi:  0.210nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088168(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahy...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50403876(CHEMBL323098)
Affinity DataKi:  0.330nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408130(CHEMBL35926)
Affinity DataKi:  0.350nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088161(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahy...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088161(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahy...)
Affinity DataKi:  0.420nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50403877(CHEMBL103105)
Affinity DataKi:  0.710nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408876(CHEMBL434602)
Affinity DataKi:  0.780nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088164((S)-2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cy...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088164((S)-2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cy...)
Affinity DataKi:  0.780nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408122(CHEMBL37106)
Affinity DataKi:  1.10nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408872(CHEMBL58548)
Affinity DataKi:  1.10nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408871(CHEMBL60700)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049170((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataKi:  2nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408135(CHEMBL288666)
Affinity DataKi:  2nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408877(CHEMBL412127)
Affinity DataKi:  2nMAssay Description:Compound was tested for the binding affinity against thymidylate synthase from L1210 mouse leukemia cells; value given as 0.9, 2.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50403878(CHEMBL320651)
Affinity DataKi:  2.10nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088157(2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclop...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408874(CHEMBL299062)
Affinity DataKi:  2.20nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408873(CHEMBL292920)
Affinity DataKi:  2.40nMAssay Description:Compound was tested for the binding affinity against thymidylate synthase from L1210 mouse leukemia cells; value given as 2.4,1.8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088169(4-(2-Benzenesulfonylamino-1-methyl-2-oxo-ethylcarb...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408875(CHEMBL57549)
Affinity DataKi:  2.60nMAssay Description:Binding affinity against thymidylate synthase from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408136(CHEMBL291084)
Affinity DataKi:  2.60nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408129(CHEMBL289749)
Affinity DataKi:  3nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50403880(CHEMBL317717)
Affinity DataKi:  3.5nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408127(CHEMBL264609)
Affinity DataKi:  4nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408123(CHEMBL36433)
Affinity DataKi:  8.20nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408126(CHEMBL36721)
Affinity DataKi:  8.60nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408125(CHEMBL288615)
Affinity DataKi:  11nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408133(CHEMBL287693)
Affinity DataKi:  18nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataKi:  20nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408131(CHEMBL36426)
Affinity DataKi:  23nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408132(CHEMBL284613)
Affinity DataKi:  35nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408124(CHEMBL34857)
Affinity DataKi:  42nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50408134(CHEMBL35941)
Affinity DataKi:  50nMAssay Description:Inhibition of Thymidylate Synthase(TS) from mouse L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Mus musculus)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50403881(CHEMBL102954)
Affinity DataKi:  1.20E+3nMAssay Description:Tested for inhibitory activity against thymidylate synthase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReduced folate transporter(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataKi:  3.50E+3nMAssay Description:Affinity towards RFC measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088164((S)-2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cy...)
Affinity DataKi:  6.00E+3nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088157(2-{4-[(2-Methyl-4-oxo-4,6,7,8-tetrahydro-3H-cyclop...)
Affinity DataKi:  1.40E+4nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088169(4-(2-Benzenesulfonylamino-1-methyl-2-oxo-ethylcarb...)
Affinity DataKi:  4.00E+4nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088168(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahy...)
Affinity DataKi:  6.90E+4nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088159(4-[3-Carboxy-1-(1H-tetrazol-5-yl)-propylcarbamoyl]...)
Affinity DataKi:  1.06E+5nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50088161(2-(4-Carboxy-4-{4-[(2-methyl-4-oxo-4,6,7,8-tetrahy...)
Affinity DataKi:  1.50E+5nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50049170((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...)
Affinity DataKi:  2.00E+5nMAssay Description:Affinity towards RFC (Reduced folate carrier) measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50075437(2,4,5-Trifluoro-6-nitro-3-((2E,6E)-3,7,11-trimethy...)
Affinity DataIC50:  6.30E+3nMAssay Description:In vitro inhibition of rat brain cytosol farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50075437(2,4,5-Trifluoro-6-nitro-3-((2E,6E)-3,7,11-trimethy...)
Affinity DataIC50:  1.25E+4nMAssay Description:In vitro inhibition of rat brain cytosol Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50075439(3-Benzyloxy-2,4,5-trifluoro-6-nitro-phenol | CHEMB...)
Affinity DataIC50:  5.80E+4nMAssay Description:In vitro inhibition of rat brain cytosol Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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