TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Rattus norvegicus (Rat))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [33P]S1P from human S1P2 expressed in CHO-K1 cells by scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Rattus norvegicus (Rat))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Rattus norvegicus (Rat))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Rattus norvegicus (Rat))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Antagonist activity at human S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Displacement of [125I]CRF from rat CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 11.6nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antagonist activity at S1P2 receptor (unknown origin) expressed in CHO cells assessed as inhibition of S1P-induced increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 2(Rattus norvegicus (Rat))
Ono Pharmaceutical
Curated by ChEMBL
Ono Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonist activity at rat S1P2 expressed in CHO cells assessed as Ca2+ level by FURA-2AM dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHOK1 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 13.1nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute
Curated by ChEMBL
Minase Research Institute
Curated by ChEMBL
Affinity DataIC50: 13.4nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair