Found 132 with Last Name = 'namanja' and Initial = 'a' 
Affinity DataIC50: 240nMAssay Description:Displacement of [125I]-iodoarylazidoprazosin from human P-gp expressed in baculovirus-infected insect Sf9 cells incubated for 10 mins followed by UV ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 1.10E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 1.10E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 1.42E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 1.42E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 1.60E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 1.60E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 1.86E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 1.88E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.00E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.08E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.10E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 2.15E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.15E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.30E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 2.32E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.32E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 1(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.50E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of P-gp overexpressed in human 12D7-MDR cells assessed as inhibition of calcein-AM efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 2.70E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.70E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 2.90E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 3.00E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 3.00E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 3.42E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 3.42E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City of Hope
US Patent
City of Hope
US Patent
Affinity DataIC50: 3.62E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 3.62E+3nMpH: 7.4Assay Description:Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetSentrin-specific protease 2(Homo sapiens (Human))
Beckman Research Institute of The City of Hope
Beckman Research Institute of The City of Hope
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of P-gp in human CMEC/D3 cells assessed as inhibition of NBD-Aba efflux after 30 mins by flow cytometryMore data for this Ligand-Target Pair
