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TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451408(US10710967, Example 2)
Affinity DataIC50:  0.0100nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451407(US10710967, Example 1)
Affinity DataIC50:  0.0200nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451438(US10710967, Example 20)
Affinity DataIC50:  0.0600nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451427(US10710967, Example 22)
Affinity DataIC50:  0.110nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451477(US10710967, Example 74)
Affinity DataIC50:  0.110nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451447(US10710967, Example 43)
Affinity DataIC50:  0.130nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274454(CHEMBL511107 | FGGFTGARKSARKKKNQ)
Affinity DataIC50:  0.160nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451418(US10710967, Example 12)
Affinity DataIC50:  0.180nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274449(CHEMBL505874 | FGGFTGARKSARKRKNQ)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274452(CHEMBL506825 | FGGFTGARKSARKKRNQ)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50333104(CHEMBL389521 | H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2...)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [3H]nociceptin from recombinant ORL1 receptor expressed in COS7 cells by competitive receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274449(CHEMBL505874 | FGGFTGARKSARKRKNQ)
Affinity DataIC50:  0.210nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296841(CHEMBL556388 | FGGFTGARKSARKWRNQ)
Affinity DataIC50:  0.230nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296842(CHEMBL559130 | FGGFTGARKSARKWKNQ)
Affinity DataIC50:  0.25nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274453(CHEMBL507847 | FGGFTGARKSARKRRNQ)
Affinity DataIC50:  0.270nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296843(CHEMBL555757 | FGGFTGARKSARKRWNQ)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50296844(CHEMBL558807 | FGGFTGARKSARKKWNQ)
Affinity DataIC50:  0.310nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274462(CHEMBL526333 | FGGFTGARKSARKLRNQ)
Affinity DataIC50:  0.310nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451429(US10710967, Example 24)
Affinity DataIC50:  0.310nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274455(CHEMBL500773 | FGGFTGARKSARKRANQ)
Affinity DataIC50:  0.330nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274456(CHEMBL505632 | FGGFTGARKSARKKANQ)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274463(CHEMBL503512 | FGGFTGARKSARKLKNQ)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274461(CHEMBL504587 | FGGFTGARKSARKWANQ)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274461(CHEMBL504587 | FGGFTGARKSARKWANQ)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274451(CHEMBL505824 | FGGFTGARKSARKRKRK)
Affinity DataIC50:  0.420nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274464(CHEMBL504872 | FGGFTGARKSARKLLNQ)
Affinity DataIC50:  0.480nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451413(US10710967, Example 7)
Affinity DataIC50:  0.480nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451409(US10710967, Example 3)
Affinity DataIC50:  0.480nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274450(CHEMBL499157 | FGGFTGARKSARKLARK)
Affinity DataIC50:  0.540nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50333104(CHEMBL389521 | H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]nociceptin from human ORL1-Galpha fusion receptor in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50372279(CHEMBL271478)
Affinity DataIC50:  0.660nMAssay Description:Displacement of [3H]nociceptin from human ORL1-Galpha fusion receptor in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.670nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  0.720nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50333104(CHEMBL389521 | H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2...)
Affinity DataIC50:  0.720nMAssay Description:Displacement of [3H]nociceptin from recombinant ORL1 receptor expressed in COS7 cells by competitive receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50333104(CHEMBL389521 | H-FGGFTGARKSARKLANQ-NH2 | N/OFQ-NH2...)
Affinity DataIC50:  0.730nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451449(US10710967, Example 45)
Affinity DataIC50:  0.760nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451558(US10710967, Example 157)
Affinity DataIC50:  0.780nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50372278(CHEMBL256055)
Affinity DataIC50:  0.790nMAssay Description:Displacement of [3H]nociceptin from human ORL1-Galpha fusion receptor in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451423(US10710967, Example 17)
Affinity DataIC50:  0.860nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451426(US10710967, Example 21)
Affinity DataIC50:  0.880nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274448(CHEMBL504461 | FGGFTGARKRKRKLANQ)
Affinity DataIC50:  0.940nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451699(US10710967, Example 294)
Affinity DataIC50: <1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451658(US10710967, Example 256)
Affinity DataIC50:  1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451657(US10710967, Example 255)
Affinity DataIC50: <1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451642(US10710967, Example 240)
Affinity DataIC50: <1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451640(US10710967, Example 238)
Affinity DataIC50: <1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451639(US10710967, Example 237)
Affinity DataIC50: <1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451637(US10710967, Example 235)
Affinity DataIC50:  1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E synthase(Homo sapiens (Human))
Aska Pharmaceutical

US Patent
LigandPNGBDBM451635(US10710967, Example 233)
Affinity DataIC50: <1nMAssay Description:Microsomes were prepared from COS-1 cells transiently transfected with a plasmid containing human mPGES-1 cDNA, and used as mPGES-1 enzyme. The mPGES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50274466(CHEMBL525604 | FGGFTGARKSARKLFNQ)
Affinity DataIC50:  1nMAssay Description:Displacement of [3H]nociceptin from rat ORL1 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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