Affinity DataKi: 0.300nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Inhibition of Protein kinase C eta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of equine serum BChE using varying levels of butyrylthiocholine iodide as substrate by Line weaver Burk reciprocal plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 119nMAssay Description:Inhibition of Protein kinase C eta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Inhibition of equine serum BChE using varying levels of butyrylthiocholine iodide as substrate by Line weaver Burk reciprocal plot analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataKi: 312nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibition of Protein kinase C delta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 884nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Protein kinase C alpha expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of Protein kinase C eta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of Protein kinase C eta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of horse serum BChE using butrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 min...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataIC50: 12.7nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of Protein kinase C eta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition by El...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 32nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 45nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Ligand Info
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 59nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 120nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
Affinity DataIC50: 199nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 270nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of HIV-1 reverse transcriptase after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition by ...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of Protein kinase C eta expressed in Sf-9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology
Curated by ChEMBL
Wuhan University of Technology
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant 6His-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) autophosphorylation expressed in baculovirus in...More data for this Ligand-Target Pair
Ligand Info
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 510nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 570nMpH: 8.0 T: 2°CAssay Description:This spectrophotometric assay is based on the reaction of
5,5-dithio-bis(2-nitrobenzoic)acid (DTNB) with thiocholine to yield a
colored product. Sh...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Tested for inhibition of cGMP-dependent protein kinase from bovine lungMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Anhui Medical University
Curated by ChEMBL
Anhui Medical University
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured for 10 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Wuhan University Of Technology
Curated by ChEMBL
Wuhan University Of Technology
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant human COX2 by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair