Affinity DataKi: 6nMAssay Description:Inhibition of human AICARFTMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 binding to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 0.520nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of binding of [125I]- Bolton-Hunter labeled CCK-8 to CCK-B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 binding to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 binding to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant HDAC1 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant HDAC2 using fluor de Lys as substrate by fluorometric analysisMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Jena
Curated by ChEMBL
University Of Jena
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of BChE in equine serum using butyrylthiocholine iodide substrate by Ellman assayMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Inhibition of rat microsomal HMGCoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 of liver microsomes isolated from cholesterol-fed rats.More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligandMore data for this Ligand-Target Pair