Affinity DataIC50: 0.800nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC3 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC4 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC2 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC9 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 31.6nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC3 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Glaxo Wellcome Research And Development
Curated by ChEMBL
Glaxo Wellcome Research And Development
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC3 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC7 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC9 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC8 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC1 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC4 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC4 by in vitro deacetylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...More data for this Ligand-Target Pair
TargetBromodomain adjacent to zinc finger domain protein 2A(Homo sapiens (Human))
Gsk
Curated by ChEMBL
Gsk
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of BAZ2A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair