Compile Data Set for Download or QSAR
maximum 50k data
Found 1609 with Last Name = 'zou' and Initial = 'l'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50312599(CHEMBL1093735 | N-Cyclohexyl-4-[(2,4-dichloropheny...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355892(CHEMBL1910035)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355891(CHEMBL1910034)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154561(CHEMBL3774603)
Affinity DataKi:  42nMAssay Description:Competitive inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450436(CHEMBL4173663)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)
Affinity DataKi:  68nMAssay Description:Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571105(CHEMBL4851375)
Affinity DataKi:  90nMAssay Description:Non-competitive inhibition of CES2 in human liver microsomes using fluorescein diacetate as substrate by Lineweaver-Burk plot based Michelis-Menten e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450440(CHEMBL4170829)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450439(CHEMBL4162307)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450437(CHEMBL4177037)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM404212((2S,5R)-5-(2-chlorophenyl)-1-(2'-cyano-4'-methoxy-...)
Affinity DataKi: <200nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450289(CHEMBL4172928)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408766((2S,5R)-1-(1-(5-chloro-2-nitrophenyl)piperidine-4-...)
Affinity DataKi: <200nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355892(CHEMBL1910035)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355891(CHEMBL1910034)
Affinity DataKi:  242nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50584760(CHEMBL2068968)
Affinity DataKi:  250nMAssay Description:Inactivation of recombinant human CYP3A4 assessed as inhibition constant using midazolam as substrate preincubated for 5 mins followed by beta-NADP a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450441(CHEMBL4173387)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450435(CHEMBL4165748)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50312599(CHEMBL1093735 | N-Cyclohexyl-4-[(2,4-dichloropheny...)
Affinity DataKi:  329nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells pretreated for 10 mins measured after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450438(CHEMBL4166818)
Affinity DataKi:  398nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408762((2S,5R)-5-(2-chlorophenyl)-1-(1-(2-cyano-4-nitroph...)
Affinity DataKi:  600nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM404212((2S,5R)-5-(2-chlorophenyl)-1-(2'-cyano-4'-methoxy-...)
Affinity DataKi:  600nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408761((2S,5R)-5-(2-chlorophenyl)-1-(1-(4-methyl-2-nitrop...)
Affinity DataKi:  600nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50584760(CHEMBL2068968)
Affinity DataKi:  660nMAssay Description:Inactivation of CYP3A4 in human liver microsomes assessed as inhibition constant using midazolam as substrate preincubated for 5 mins followed by bet...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450443(CHEMBL4174307)
Affinity DataKi:  794nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM404211((2S,5R)-5-(2-cyanophenyl)-1-(2'-methoxy-[1,1'-biph...)
Affinity DataKi: <1.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408758( (2S,5R)-5-(2-chlorophenyl)-1-(1-(4-(morpholinosul...)
Affinity DataKi: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408760((2S,5R)-5-(2-chlorophenyl)-1-(1-(4-(N,N-diethylsul...)
Affinity DataKi: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408767((2S,5R)-5-(2-chlorophenyl)-1-(1-(2-nitrophenyl)pip...)
Affinity DataKi: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408765( (2S,5R)-5-(2-chlorophenyl)-1-(1-(3-methoxy-4-nitr...)
Affinity DataKi: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408763( (2S,5R)-5-(2-chlorophenyl)-1-(1-(4-nitrophenyl)pi...)
Affinity DataKi: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408764((2S,5R)-5-(2-chlorophenyl)-1-(1-(2-fluoro-4-nitrop...)
Affinity DataKi: >1.00E+3nMAssay Description:The [35S]GTPγS assay was incubated in 20 mM HEPES pH7.4, 100 mM NaCl, 10 μg/ml saponin, 30 mM of MgCl2, 10 μM of GDP, 5 μg membra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408766((2S,5R)-1-(1-(5-chloro-2-nitrophenyl)piperidine-4-...)
Affinity DataKi: <1.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50584761(BUFALIN | Bufalin | CHEBI:517248)
Affinity DataKi:  1.13E+3nMAssay Description:Inactivation of recombinant human CYP3A4 assessed as inhibition constant using midazolam as substrate preincubated for 5 mins followed by beta-NADP a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human CES2A using 4-methylumbelliferone as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408762((2S,5R)-5-(2-chlorophenyl)-1-(1-(2-cyano-4-nitroph...)
Affinity DataKi:  1.50E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM404212((2S,5R)-5-(2-chlorophenyl)-1-(2'-cyano-4'-methoxy-...)
Affinity DataKi:  1.50E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408761((2S,5R)-5-(2-chlorophenyl)-1-(1-(4-methyl-2-nitrop...)
Affinity DataKi:  1.50E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450434(CHEMBL4172349)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408758( (2S,5R)-5-(2-chlorophenyl)-1-(1-(4-(morpholinosul...)
Affinity DataKi: >2.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408765( (2S,5R)-5-(2-chlorophenyl)-1-(1-(3-methoxy-4-nitr...)
Affinity DataKi: >2.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408764((2S,5R)-5-(2-chlorophenyl)-1-(1-(2-fluoro-4-nitrop...)
Affinity DataKi: >2.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408763( (2S,5R)-5-(2-chlorophenyl)-1-(1-(4-nitrophenyl)pi...)
Affinity DataKi: >2.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408767((2S,5R)-5-(2-chlorophenyl)-1-(1-(2-nitrophenyl)pip...)
Affinity DataKi: >2.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM408760((2S,5R)-5-(2-chlorophenyl)-1-(1-(4-(N,N-diethylsul...)
Affinity DataKi: >2.00E+3nMAssay Description:Human GPR43 radioligand binding assay is performed by adding successively in the wells of a 96 well plate (Master Block, Greiner, 786201), 50 ul of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFree fatty acid receptor 2(Homo sapiens (Human))
Ogeda

Curated by ChEMBL
LigandPNGBDBM50450442(CHEMBL4170872)
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]ES227703 from human FFA2R expressed in CHOK1 cells after 60 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Shanghai University Of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50584761(BUFALIN | Bufalin | CHEBI:517248)
Affinity DataKi:  2.09E+4nMAssay Description:Inactivation of CYP3A4 in human liver microsomes assessed as inhibition constant using midazolam as substrate preincubated for 5 mins followed by bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50355892(CHEMBL1910035)
Affinity DataIC50:  0.900nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP55940-induced Ca2+ release afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCREB-binding protein(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50602881(CHEMBL5204688)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCREB-binding protein(Homo sapiens (Human))
Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50602873(CHEMBL5191045)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of His6-tagged human CBP bromodomain (1081 to 1197 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Displayed 1 to 50 (of 1609 total ) | Next | Last >>
Jump to: