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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
25
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.00300nM
Assay Description:
Binding affinity towards rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus oocytes using [3H]-epibatidine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cholinergic receptor, nicotinic, alpha 1 (Muscle) isoform X1
(Xenopus)
University of Miami
Curated by
PDSP K
i
Database
Ligand
BDBM86042
(NEP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.00310nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
neuronal acetylcholine receptor subunit alpha-4
(Xenopus)
University of Miami
Curated by
PDSP K
i
Database
Ligand
BDBM86042
(NEP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.00850nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.00900nM
Assay Description:
Binding affinity towards rat Nicotinic acetylcholine receptor alpha3-beta2 expressed in Xenopus oocytes using [3H]-epibatidine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0200nM
Assay Description:
Inhibition of [3H]-nicotine binding to alpha4-beta2 nACh receptor from rat membranes from ref 16
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
PDSP K
i
Database
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0200nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0200nM
Assay Description:
Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortex
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0200nM
Assay Description:
Functional potency measured as stimulation at rat Nicotinic acetylcholine receptor alpha4-beta4 expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0260nM
Assay Description:
In vitro binding affinity towards (alpha-4)2(beta-2)3 neuronal nicotinic acetylcholine receptor in P2 membrane fractions of rat forebrain
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-2/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0280nM
Assay Description:
Binding affinity towards rat alpha2-beta2 neuronal nAChR expressed in Xenopus oocytes using [3H]-epibatidine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
neuronal acetylcholine receptor subunit alpha-2
(Xenopus)
University of Miami
Curated by
PDSP K
i
Database
Ligand
BDBM86042
(NEP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0280nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0310nM
Assay Description:
Non-specific binding in presence of 300 uM nicotine at nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0640nM
Assay Description:
Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenates
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.0640nM
Assay Description:
Displacement of [3H]-cytisine from Alpha4-beta2 Nicotinic acetylcholine receptor of rat brain homogenates
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.20nM
Assay Description:
Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinergic receptor, nicotinic alpha 1
(Xenopus)
University of Miami
Curated by
PDSP K
i
Database
Ligand
BDBM86042
(NEP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.20nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
neuronal acetylcholine receptor subunit alpha-2
(Xenopus)
University of Miami
Curated by
PDSP K
i
Database
Ligand
BDBM86042
(NEP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.30nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-2/beta-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.30nM
Assay Description:
Binding affinity towards rat Nicotinic acetylcholine receptor alpha2-beta4 expressed in Xenopus oocytes using [3H]-epibatidine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinergic receptor nicotinic alpha 5 subunit
(Xenopus)
University of Miami
Curated by
PDSP K
i
Database
Ligand
BDBM86042
(NEP)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranes from ref 15
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 982nM
Assay Description:
Inhibition of [3H]-epibatidine binding to alpha4-beta2 nACh receptor from rat membranes from ref 16
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 510nM
Assay Description:
Effective concentration against alpha3-beta4 nicotinic acetylcholine receptor (nAChR) expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 702nM
Assay Description:
Binding affinity towards rat Nicotinic acetylcholine receptor alpha4-beta2 expressed in Xenopus oocytes using [3H]-epibatidine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-4
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 510nM
Assay Description:
Effective concentration against alpha3-beta4 nicotinic acetylcholine receptor (nAChR) expressed in Xenopus oocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
Research Triangle Institute
Curated by
ChEMBL
Ligand
BDBM50100717
(2-(pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | 2-P...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.63E+3nM
Assay Description:
Binding affinity towards rat alpha2-beta2 neuronal nAChR expressed in Xenopus oocytes using [3H]-epibatidine as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI