Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
375
hits in this display
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.20nM
Assay Description:
Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.80nM
Assay Description:
Binding Affinity on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexole was tested
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90nM
Assay Description:
Displacement of [3H]-quinpirole from human dopamine D2A receptors expressed in LtK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90nM
Assay Description:
Displacement of [3H]-quinpirole from Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2nM
Assay Description:
Displacement of [3H]-raclopride from high-affinity state of human dopamine D2L receptor (443 amino acids) expressed in LTK deficient mouse fibroblast...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.80nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.90nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3nM
Assay Description:
Displacement of [3H]-(R)-(+)-7-OH-DPAT from human dopamine D3 receptor expressed in HEK293 cell membranes after 90 mins by micro beta scintillation c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.20nM
Assay Description:
Displacement of [3H]spiperone from human D4 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7nM
Assay Description:
Binding Affinity was tested on High Affinity Site of Bovine Dopamine receptor D1. Tested for ability to displace the radioligand [3H]-SCH- 23390
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Dopamine receptor D4
(CANINE)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.5nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.60nM
Assay Description:
Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8nM
Assay Description:
Displacement of [3H]-NPA from dopamine D2L receptor (unknown origin) expressed in CHO cell membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.70nM
Assay Description:
Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Binding Affinity was tested on high Affinity Site of Bovine Dopamine D2 Receptor. Tested for ability to displace the radioligand [3H]spiperone was te...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
Binding affinity which represents concentration giving half-maximal inhibition of [3H]7-OH-DPAT binding to Dopamine receptor D3 in rat tissue homogen...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11.7nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 13.2nM
Assay Description:
Displacement of [3H]-raclopride from Dopamine receptor D3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Inhibition of [3H]YM-09151-2 binding to bovine retina membrane Dopamine receptor D2, high affinity site
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
In vitro affinity against Dopamine receptor D2 using [3H]DP-5,6-ADTN radioligand in rat striatal homogenate.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Displacement of [3H]raclopride from human D3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 16nM
Assay Description:
Displacement of [3H]-(R)-(+)-7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membranes after 90 mins by micro beta scintillation c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 16.8nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 17nM
Assay Description:
Binding Affinity on High Affinity Site of Dopamine receptor D2S
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 17.5nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
Assay Description:
Displacement of [3H]YM-09151-2 from human dopamine D3 receptor expressed in CHOp cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 20nM
Assay Description:
Binding affinity on High Affinity Site of Dopamine receptor D2L
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 21nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 22nM
Assay Description:
Displacement of [3H]-iodosulpiride from cloned human dopamine D2S receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 23nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 25nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Dopamine receptor D4
(CANINE)
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 28nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 29nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 33.9nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 34nM
Assay Description:
High binding affinity of the compound for dopamine D-2 receptor from bovine anterior pitutary membrane, using radioligand [3H]-spiroperidol
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 34nM
Assay Description:
Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2S
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 36nM
Assay Description:
Binding Affinity was tested on relative proportion of High Affinity Site of Bovine dopamine receptor D1. Tested for ability to displace the radioliga...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Nih
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 38.3nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Norepinephrine transporter
(RAT)
Nih
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 40.3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 42nM
Assay Description:
Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2L
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 42.9nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 48nM
Assay Description:
Displacement of [3H]spiperone from human D2S receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 49nM
Assay Description:
Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 50nM
Assay Description:
Binding Affinity was tested on the high affinity site of Dopamine receptor D3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 51nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 51nM
Assay Description:
Binding Affinity was tested on relative proportion of high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioliga...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 51.4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 52nM
Assay Description:
Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 55.0nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 56nM
Assay Description:
Displacement of [3H]-iodosulpiride from recombinant high-affinity state of human dopamine D2L receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 57nM
Assay Description:
Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D4.4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 62nM
Assay Description:
Binding Affinity was tested on low Affinity Site of Dopamine receptor D4.4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 67nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 72nM
Assay Description:
Displacement of [3H]spiperone from human wild type D3 receptor expressed in human HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 97nM
Assay Description:
Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D4.4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 101nM
Assay Description:
Displacement of [3H]spiperone from rat D3 dopamine receptor expressed in HEK293 cell membranes after 1 hr
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 101nM
Assay Description:
Displacement of [3H]Spiroperidol from cloned rat dopamine D3 receptor expressed in HEK293 cells by liquid scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 104nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 105nM
Assay Description:
Binding affinity against Dopamine receptor D2 in rat striatal membranes using [3H]spiperone
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 110nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 124nM
Assay Description:
Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in Ltk deficient fibroblast cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 130nM
Assay Description:
Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 150nM
Assay Description:
Displacement of [3H]fenoldopam from Dopamine receptor D1 of rat striatum membranes
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 180nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 190nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 192nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 192nM
Assay Description:
Binding affinity to displace [3H]- SCH 23390 against Dopamine receptor D1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 197nM
Assay Description:
Displacement of [3H]raclopride from rat dopamine D2short receptor expressed in CHO-K1 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(RABBIT)
University of California
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 200nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 210nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 211nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 220nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1B) dopamine receptor
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 228nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Nih
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 230nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 231nM
Assay Description:
Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 231nM
Assay Description:
Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 240nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 240nM
Assay Description:
Displacement of [3H]spiperone from human D3 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 243nM
Assay Description:
Displacement of [3H]-SCH23390 from human dopamine D1 receptor expressed in LTK cell membranes after 30 mins by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(RABBIT)
University of California
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 250nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 250nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 260nM
Assay Description:
Binding affinity against cloned human Dopamine receptor D2 using [3H]spiperone as radioligand transfected in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 266nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 290nM
Assay Description:
Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 293nM
Assay Description:
Displacement of [3H]N-methylspiperone from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 296nM
Assay Description:
Inhibitory constant against binding of [125I]- IBZM to rat striatal membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 309nM
Assay Description:
Binding affinity against Dopamine receptor D1 in rat striatal membranes using [3H]SCH-23390
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 310nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
The University of Queensland
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 323nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 360nM
Assay Description:
Displacement of [3H]spiperone from human D2short receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 380nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Norepinephrine transporter
(RAT)
Nih
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 392nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(BOVINE)
The University of Queensland
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 397nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 407nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 417nM
Assay Description:
Binding Affinity was determined against Dopamine receptor D1 in rat striatal membranes using [3H]- SCH 23390 radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 422nM
Assay Description:
Displacement of [3H]YM-09151-2 from human dopamine D2 receptor expressed in CHOp cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 422nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Trace amine-associated receptor 1
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 422nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 440nM
Assay Description:
Displacement of [3H]SCH23390 from dopamine D1 receptor in bovine striatum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 450nM
Assay Description:
Displacement of [3H]spiperone from human D2long receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 474nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 474nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 475nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 475nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 544nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 545nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 545nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 550nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 550nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 572nM
Assay Description:
Inhibition of [3H]-raclopride binding to Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 594nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 617nM
Assay Description:
Tested for binding affinity against Dopamine receptor D2 like from bovine striatum membranes by using [3H]YM-09151-2 radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 650nM
Assay Description:
Binding Affinity was tested on low Affinity Site of Bovine Dopamine D1 Receptor. Tested for ability to displace the radioligand [3H]-SCH- 23390 at th...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 660nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 670nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 700nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 700nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 710nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 724nM
Assay Description:
Binding Affinity was determined against Dopamine receptor D2 in rat striatal membranes using [3H]- spiperone radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 759nM
Assay Description:
Displacement of [3H]-raclopride from human dopamine D2A receptors expressed in LtK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 843nM
Assay Description:
Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 871nM
Assay Description:
Displacement of [3H]spiperone from low-affinity state of human dopamine D2S receptor transfected in HEK293 cells after 2 hrs by scintillation countin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 880nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 920nM
Assay Description:
Displacement of [3H]spiperone from low-affinity state of human dopamine D2S receptor transfected in HEK293 cells after 2 hrs by scintillation countin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Adenosine receptor A2b
(Rattus norvegicus)
TBA
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 977nM
Assay Description:
Compound was tested for its binding affinity against Alpha-2 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 990nM
Assay Description:
Displacement of [3H]spiperone from rat D2L dopamine receptor expressed in HEK293 cell membranes after 1 hr
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 990nM
Assay Description:
Displacement of [3H]Spiroperidol from cloned rat dopamine D2L receptor expressed in HEK293 cells by liquid scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity at Dopamine receptor D1 in rat neostriatum by [3H]-SCH- 23390 displacement.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+3nM
Assay Description:
Binding affinity at Dopamine receptor D2 in rat striatal homogenate by [3H]-spiperone displacement.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
CB1 cannabinoid receptor-interacting protein 1
(theromyzon Tessulatum)
State University of New York At Old Westbury
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cannabinoid receptor 1
(Hirudo medicinalis)
State University of New York At Old Westbury
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 5B
(RAT)
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 5A
(RAT)
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 5B
(RAT)
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Norepinephrine transporter
(RAT)
Nih
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.10E+3nM
Assay Description:
Binding Affinity of Compound of Dopamine receptor D2S
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.45E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.52E+3nM
Assay Description:
Inhibition of [3H]YM-09151-2 binding to bovine retina membrane Dopamine receptor D2, low affinity site
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+3nM
Assay Description:
Binding Affinity was determined for its ability to displace the radioligand [3H]spiperone from low Affinity Site of Bovine dopamine receptor D2.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+3nM
Assay Description:
Binding Affinity was determined for its ability to displace the radioligand [3H]-SCH- 23390 from Bovine dopamine receptor D1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.60E+3nM
Assay Description:
Binding Affinity was tested on low Affinity Site of Dopamine receptor D3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.61E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.77E+3nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90E+3nM
Assay Description:
Binding Affinity was tested on low Affinity Site of Dopamine receptor D2L
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Mus musculus (Mouse))
Medical Research Service
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.95E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10E+3nM
Assay Description:
Displacement of [3H]raclopride from human dopamine D2L receptor expressed in HEK293 cells by scintillation counting analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10E+3nM
Assay Description:
Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.10E+3nM
Assay Description:
Displacement of [3H]raclopride from human D2L receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.34E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.35E+3nM
Assay Description:
Compound was tested for inhibition of [3H]spiroperidol binding against Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1B) dopamine receptor
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.44E+3nM
Assay Description:
Inhibitory constant for [3H]SCH-23390 binding to Dopamine receptor D1-like of porcine striatal membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Homo sapiens (Human))
TBA
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.51E+3nM
Assay Description:
Compound was tested for its binding affinity against Alpha-1 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.63E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.10E+3nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.31E+3nM
Assay Description:
Inhibitory constant for [3H]YM-09151-2 binding to Dopamine receptor D2-like in porcine striatal membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.38E+3nM
Assay Description:
Low binding affinity of the compound for dopamine D-2 receptor from bovine anterior pitutary membrane, using radioligand [3H]-spiroperidol
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.69E+3nM
Assay Description:
Displacement of [3H]N-methylspiperone from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1B) dopamine receptor
(RAT)
Duke University
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.90E+3nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.30E+3nM
Assay Description:
Binding affinity against Dopamine receptor D1 like from bovine retina membranes measured using [3H]SCH-23390 radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.30E+3nM
Assay Description:
Binding affinity for dopamine D1-like receptor labelled with [3H]SCH-23390 in retina
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.40E+3nM
Assay Description:
In vitro affinity against Dopamine receptor D1 using [3H]SCH-23390 radioligand in rat striatal homogenate.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.47E+3nM
Assay Description:
Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in LHD1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.47E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Nih
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >5.00E+3nM
Assay Description:
Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.30E+3nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.90E+3nM
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.40E+3nM
Assay Description:
Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cells
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
Novo Industri
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.49E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melatonin receptor type 1A
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.10E+3nM
Assay Description:
Displacement of 2-[125I]-Iodomelatonin from human Melatonin receptor type 1A expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(RABBIT)
University of Montana
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.80E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.94E+3nM
Assay Description:
Affinity towards Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.25E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 8.91E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Melatonin receptor type 1B
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.10E+3nM
Assay Description:
Inhibition of 2-[125I]-Iodomelatonin binding to human Melatonin receptor type 1B expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Alpha-2C adrenergic receptor
(RAT)
University of California
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.99E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+4nM
Assay Description:
Binding of [3H]-dihydroalprenolol to beta-1 adrenergic receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(MOUSE)
Cnrs
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(CANINE)
University of Pennsylvania
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Alpha-2C adrenergic receptor
(RAT)
University of California
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sigma non-opioid intracellular receptor 1
(RAT)
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [125I]trans-8-OH-PIPAT in membrane homogenates of hippocampal tissue ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 5B
(MOUSE)
Cnrs
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 5A
(MOUSE)
Cnrs
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
5-hydroxytryptamine receptor 5A
(MOUSE)
Cnrs
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.16E+4nM
Assay Description:
Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.16E+4nM
Assay Description:
Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.20E+4nM
Assay Description:
Displacement of [3H]SCH23390 from human D1 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.50E+4nM
Assay Description:
Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D2L
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.50E+4nM
Assay Description:
Binding Affinity was determined in the presence of 100 micro M Gpp(NH)p for decoupling of the ternary complex of Compound to Dopamine receptor D2S
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.82E+4nM
Assay Description:
Affinity towards Dopamine receptor D1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
The University of Queensland
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >2.80E+4nM
Assay Description:
Displacement of [125I]RT155 binding in HEK cells expressing human NET
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Rattus norvegicus (Rat))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.40E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Canis familiaris)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.00E+4nM
Assay Description:
Binding of [3H]-dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.10E+4nM
Assay Description:
Displacement of [3H]CGP12177 from human beta2 receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Solute carrier family 22 member 2
(RAT)
Kyoto University Hospital
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.47E+5nM
Assay Description:
TP_TRANSPORTER: inhibition of TEA uptake in OCT2-expressing MDCK cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Solute carrier family 22 member 1
(RAT)
Kyoto University Hospital
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.03E+5nM
Assay Description:
TP_TRANSPORTER: inhibition of TEA uptake in OCT1-expressing MDCK cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.10E+6nM
Assay Description:
Displacement of [125I]RT155 binding in HEK cells expressing human SERT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.20E+7nM
Assay Description:
Binding Affinity was determined for its ability to displace the radioligand [3H]spiperone from Bovine dopamine receptor D1.
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0nM
Assay Description:
Agonist required to inhibit Dopamine receptor D2 photoinactivation by 50% with Iodazidoclebopride using [3H]-Spiperone
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
Assay Description:
Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A)/D(2) dopamine receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.70nM
Assay Description:
Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A)/D(2) dopamine receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.5nM
Assay Description:
Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
The University of Queensland
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.60nM
Assay Description:
Ability to inhibit the binding of [H]norepinephrine to NE receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A)/D(2) dopamine receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 64nM
Assay Description:
Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 111nM
Assay Description:
Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(3) dopamine receptor
(Rattus norvegicus (Rat))
Universita' Di Siena
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 124nM
Assay Description:
Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D3 trunk/D3 tail receptor transfected in african green monkey COS7 cel...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(1A) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
Compound was evaluated in vitro for its binding affinity towards Dopamine D1 receptor using [3H]-SCH- 23390 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
Nih
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
Assay Description:
Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometry
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 460nM
Assay Description:
Inhibition of [3H]dopamine uptake in HEK cells expressing human DAT
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A)/D(2) dopamine receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 510nM
Assay Description:
Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Alpha-synuclein
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 530nM
Assay Description:
Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 6 days by thioflavin S based fluorescence assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 800nM
Assay Description:
Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Displacement of [3H]spiperone from high-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation counti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Compound was for its ability to displace [3H]-haloperidol binding to rat striatal Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+3nM
Assay Description:
Displacement of [3H]- -spiperone from Dopamine receptor D2 in rat striatum
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A)/D(2) dopamine receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.86E+3nM
Assay Description:
Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
M18 aspartyl aminopeptidase
(Plasmodium falciparum 3D7)
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.98E+3nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20E+3nM
Assay Description:
Compound was evaluated for the inhibition of [3H]spiperone binding to Dopamine receptor D2 of rat striatal membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+3nM
Assay Description:
Compound was evaluated for the inhibition of [3H]-SCH- 23390 binding to Dopamine receptor D1 of rat striatal membranes
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.05E+3nM
Assay Description:
Neuroleptic activity in terms of [3H]-spiroperidol binding in rat striatal membrane to Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor/Kappa-type opioid receptor/Mu-type opioid receptor/Sigma non-opioid intracellular receptor 1
(Rattus norvegicus (rat))
Istituto Superiore Di Sanit£
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.05E+3nM
Assay Description:
Ability to inhibit the specific binding of [3H]- dihydromorphine to opiate receptors in rat brain membrane preparation by 50%
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.14E+3nM
Assay Description:
Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D2 receptor transfected in african green monkey COS7 cells after 1 hr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.26E+3nM
Assay Description:
Displacement of [3H]nemonapride from Rattus norvegicus (rat) chimeric dopamine D2 trunk/D2 tail receptor transfected in african green monkey COS7 cel...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.50E+3nM
Assay Description:
Inhibitory activity against [3H]spiperone in Rat Striatal membrane
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.70E+3nM
Assay Description:
Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.70E+3nM
Assay Description:
Displacement of [3H]-spiroperidol from homogenized bovine pituitary Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.34E+3nM
Assay Description:
Concentration that produces 50 % displacement of specific [3H]spiroperidol binding to rat caudate membrane preparations.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.34E+3nM
Assay Description:
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Alpha-synuclein
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.10E+3nM
Assay Description:
Inhibition of human alpha-synuclein filament formation expressed in Escherichia coli BL21(DE3) cells incubated for 72 hrs by thioflavin S based fluor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(BOVINE)
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.00E+3nM
Assay Description:
Compound was evaluated in vitro for its binding affinity towards Dopamine D2 receptor using [3H]-spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(1A)/D(2) dopamine receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Tested for binding to dopamine receptor using [3H]spiroperidol as radioligand in calf caudate nucleus homogenates.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of [3H]5-HT uptake in HEK cells expressing human SERT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by
PubChem BioAssay
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.96E+4nM
Assay Description:
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Solute carrier family 22 member 3
(Rattus norvegicus)
Medical College Of Georgia
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.20E+4nM
Assay Description:
TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 1 uM) in OCT3-expressing HRPE cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.00E+4nM
Assay Description:
Ability to displace [3H]WB-4101 from rat brain alpha-1 adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of peptide EPQ (pY) EEIPI binding to Fyn protein kinase SH2 domain at 100 uM (no inhibition)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Displacement of [3H]spiperone from low-affinity state of human dopamine D2L receptor transfected in HEK293 cells after 2 hrs by scintillation countin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Arginase-1
(Bos taurus)
Univ. Bourgogne Franche-Comt�
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.28E+5nM
Assay Description:
Inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by spectroscopic analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A)/D(2) dopamine receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.50E+5nM
Assay Description:
Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Anthrax toxin receptor 2
(Homo sapiens)
Harvard Medical School
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+5nM
Assay Description:
Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Solute carrier family 22 member 3
(Rattus norvegicus)
Medical College Of Georgia
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.84E+5nM
Assay Description:
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM) in OCT3-expressing HRPE cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Rattus norvegicus)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Solute carrier family 22 member 2
(RAT)
Kyoto University Hospital
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30E+6nM
Assay Description:
TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM) in OCT2-expressing HRPE cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.780nM
Assay Description:
Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged GalphaoB ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 163nM
Assay Description:
Concentration required for the inhibitory activity against human Farnesyltransferase
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 156nM
Assay Description:
Agonist activity at ARMS2-PK2 tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of EA-tagged beta-arrestin-2 recru...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.5nM
Assay Description:
Binding affinity towards rat Alpha-1A adrenergic receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.90nM
Assay Description:
Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai2 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 226nM
Assay Description:
Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells assessed as induction of renilla luciferase 2-tagg...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.80nM
Assay Description:
Ability to displace [3H]spiperone radioligand from cloned human Dopamine receptor D2 in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 200nM
Assay Description:
Agonist activity at human D2S receptor expressed in HEK293T cell membranes coexpressing Galphao1 assessed as induction of nucleotide exchange preincu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 160nM
Assay Description:
Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 and GRK2 assessed as induction of beta-arrestin2 r...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 390nM
Assay Description:
Partial agonist activity at human D2SR expressed in HEK293T cells co-expressing (EA)beta-arrestin2 assessed as induction of beta-arrestin2 recruitmen...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 232nM
Assay Description:
Agonist activity at human dopamine D1 receptor expressed in HEK293T cells assessed as induction of cAMP levels after 30 mins by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 19nM
Assay Description:
Agonist activity at dopamine D2 receptor long isoform (unknown origin) expressed in HEK293 cells assessed as induction of calcium flux after 60 min b...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.10nM
Assay Description:
Agonist activity at dopamine D3 receptor (unknown origin) expressed in HEK293 cells assessed as induction of calcium flux after 60 mins by calcium 4-...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
Assay Description:
Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO cell membranes after 2 hrs by liquid scintillation counting method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 91nM
Assay Description:
Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in HEK293 cell membranes after 1 hr by scintillation counting method
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 183nM
Assay Description:
Agonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5.30nM
Assay Description:
Agonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 40nM
Assay Description:
Agonist activity at human D2S receptor expressed in CHOK1 cells assessed as inhibition of forskolin induced cAMP production incubated for 10 mins fol...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.990nM
Assay Description:
Agonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells assessed as increase in calcium flux incubated for 60 mins at 37 degC follo...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 55nM
Assay Description:
Agonist activity at RLuc8-fused human D3R Y198A mutant expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 and GRK3 assess...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 140nM
Assay Description:
Agonist activity at human D2R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.40E+3nM
Assay Description:
Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on beta-arrestin2 recruitment by PRESTO-Tango beta-arrestin2 rec...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.800nM
Assay Description:
Agonist activity at D2R (unknown origin) expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gi-cAMP Glosensor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1B) dopamine receptor
(Homo sapiens (Human))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2nM
Assay Description:
Agonist activity at D5R (unknown origin) expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gs-cAMP Glosensor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.80nM
Assay Description:
Agonist activity at D4R (unknown origin) expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gi-cAMP Glosensor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 44nM
Assay Description:
Agonist activity at wild type human D1R expressed in HEK293 cells assessed as effect on cAMP accumulation incubated for 10 mins by Gs-cAMP Glosensor ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.30nM
Assay Description:
Agonist activity at human D3 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 376nM
Assay Description:
Agonist activity at human D2 dopamine receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.110nM
Assay Description:
Agonist activity at human Gi/o-coupled D3 receptor expressed in HEK293T cells assessed as inhibition of isoproterenol-induced cAMP accumulation prein...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.40nM
Assay Description:
Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.10nM
Assay Description:
Agonist activity at RLuc8-fused Go-coupled human D3R expressed in HEK293 cells untagged beta1 and mVenus-tagged gamma2 measured after 5 mins in prese...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.30nM
Assay Description:
Agonist activity at RLuc8-fused human D3R expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 and GRK3 assessed as inducti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.5nM
Assay Description:
Agonist activity at human D3R expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production measured after 5 mins in prese...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 33nM
Assay Description:
Agonist activity at RLuc8-fused human D3R Y365A mutant expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 and GRK3 assess...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.90nM
Assay Description:
Agonist activity at human D3R stably expressed in CHOK1 cells assessed as increase in ERK1/2 phosphorylation measured after 15 mins by AlphaScreen su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 820nM
Assay Description:
Agonist activity at RLuc8-fused human D3R Y198A/Y365A double mutant expressed in HEK293 cells co-expressing N-terminal Venus-tagged beta-arrestin2 an...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at human D2 receptor expressed in CHO-K1 cells by calcium 4 dye based FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Trace amine-associated receptor 1
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.71E+3nM
Assay Description:
Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analys...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens)
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.891nM
Assay Description:
Agonist activity at human dopamine D3 receptor expressed in HEK293T cells assessed as GalphaoA activation preincubated for 5 mins with coelenterazine...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 15nM
Assay Description:
Agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as G0 protein activation measured after 2.5 mins by BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 21nM
Assay Description:
Agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as Gi protein activation measured after 2.5 mins by BRET assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 269nM
Assay Description:
Agonist activity at D4R (unknown origin) expressed in human HEK293T cells assessed as beta arrestin-2 recruitment measured after 2.5 mins by BRET ass...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 200nM
Assay Description:
Agonist activity at human D2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by Perkin elmer analysis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens)
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.10nM
Assay Description:
Agonist activity at human D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding by Perkin elmer analysis
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.50E+3nM
Assay Description:
Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.67E+5nM
Assay Description:
In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 4.90E+4nM
Assay Description:
In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 6.20E+3nM
Assay Description:
In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18nM
Assay Description:
Agonist activity at human D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.20nM
Assay Description:
Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5.00E+3nM
Assay Description:
Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 9.30nM
Assay Description:
Agonist activity at human dopamine D3 receptor transiently expressed in HEK293 cells co-expressing Galphao1 after 30 mins by [35S]GTPgammaS binding a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 470nM
Assay Description:
Agonist activity at human dopamine D2 short receptor transiently expressed in HEK293 cells co-expressing Galphai2 after 30 mins by [35S]GTPgammaS bin...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 6.46E+4nM
Assay Description:
Binding affinity to human adrenergic beta2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(RAT)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.40nM
Assay Description:
Agonist activity at rat D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.10nM
Assay Description:
Agonist activity at rat D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.70nM
Assay Description:
Agonist activity at ferret D4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8nM
Assay Description:
Agonist activity at ferret D2 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 209nM
Assay Description:
Agonist activity at human cloned dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.53nM
Assay Description:
Agonist activity at human cloned dopamine D3 receptor expressed in AtT-20 cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 209nM
Assay Description:
Agonist activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.53nM
Assay Description:
Agonist activity at human dopamine D3 receptor expressed in mouse ATt-20 cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5nM
Assay Description:
Agonist activity at human D2 receptor transfected in HEK293T cells by BRET based G0 activation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.80nM
Assay Description:
Agonist activity at human D3 receptor transfected in HEK293T cells by BRET based G0 activation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.70nM
Assay Description:
Agonist activity at recombinant human D2 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.70nM
Assay Description:
Agonist activity at recombinant human D3 receptor expressing in CHOp cells assessed as receptor mediated stimulation of mitogenesis measured as [3H]t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.43E+3nM
Assay Description:
Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 209nM
Assay Description:
Activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.53nM
Assay Description:
Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 209nM
Assay Description:
Agonist activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.53nM
Assay Description:
Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 209nM
Assay Description:
Agonist activity at human dopamine D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.76nM
Assay Description:
Agonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 209nM
Assay Description:
Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 4.76nM
Assay Description:
Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 20nM
Assay Description:
Agonist activity at human D1 receptor assessed as cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 37nM
Assay Description:
Agonist activity at human dopamine D1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 15 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
cAMP-regulated phosphoprotein 19
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.50E+3nM
Assay Description:
Effective concentration that gives maximal stimulation of cyclic AMP production over the concentration range tested.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 170nM
Assay Description:
Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 100nM
Assay Description:
Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.70E+4nM
Assay Description:
Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.50E+3nM
Assay Description:
Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.70E+4nM
Assay Description:
In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(RAT)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.40nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D4 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(RAT)
Abbott Laboratories
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.70nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D4 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.10nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with rat Dopamine receptor D2 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with ferret Dopamine receptor D2 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 18nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D2 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.20nM
Assay Description:
In vitro effective concentration tested on HEK293 cells co-transfected with human Dopamine receptor D4 using FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.690nM
Assay Description:
Agonist activity at D2 receptor (unknown origin) expressed in CHOK1 cells co-expressing G-alpha 15 by fluo-4 dye based FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 35nM
Assay Description:
Agonist activity at human recombinant dopamine D1 receptor expressed in CHO cells assessed as stimulation of cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 43nM
Assay Description:
Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5nM
Assay Description:
Activity at rat dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(1A) dopamine receptor
(Homo sapiens (Human))
University Of Tartu
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 120nM
Assay Description:
Activity at human dopamine D1 receptor expressed in HEK293 cells assessed as stimulation of cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
PDB
3D Structure (crystal)
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Friedrich-Alexander University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 10nM
Assay Description:
Binding affinity to human cloned dopamine D4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 218nM
Assay Description:
Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 36nM
Assay Description:
Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as increase of forskolin-induced cAMP production after 20 mins
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.631nM
Assay Description:
Agonist activity at human dopamine D2L receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 227nM
Assay Description:
Agonist activity at human dopamine D2L receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillati...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.70nM
Assay Description:
Agonist activity at dopamine D2 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 5.80nM
Assay Description:
Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTP gammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 240nM
Assay Description:
Agonist activity at human cloned dopamine D2 receptor expressed in CHO cells by [35S]GTP gammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.10nM
Assay Description:
Agonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 65nM
Assay Description:
Agonist activity at human dopamine D2 receptor expressed in CHOp cells assessed as stimulation of mitogenesis incubated for 24 hrs by [3H]thymidine i...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Adenylate cyclase type 1
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.50E+3nM
Assay Description:
Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 227nM
Assay Description:
Agonist activity at human cloned dopamine D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8.60nM
Assay Description:
Agonist activity at human cloned dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
Uppsala University
Curated by
ChEMBL
Ligand
BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 0.780nM
Assay Description:
Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged GalphaoB ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
DrugBank
MCE
KEGG
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Displayed 1 to 50 (of 375 total ) |
Next
|
Last
>>