TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 0.708nMAssay Description:Inhibition of [125I]APT binding to histamine H2 receptor in guinea pig cerebral membranes.More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]tiotidine from human histamine H2 receptorMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Ligand Info
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 2.60nMAssay Description:Inhibition of [125I]APT binding to H2 receptors in guinea pig cerebral membranes.More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 4nMAssay Description:In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal h...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Inhibition of H2 receptorMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 5.10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 5.20nMAssay Description:Inhibition of [125I]APT binding to H2 receptors in guinea pig cerebral membranes.More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 5.60nMAssay Description:Inhibition of [125I]APT binding to H2 receptors in guinea pig cerebral membranes.More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 5.70nMAssay Description:Displacement of [3H]Cimetidine from histamine H2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 5.80nMAssay Description:Displacement of [3H]Cimetidine from histamine H2 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 6.30nMAssay Description:In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal h...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 6.30nMAssay Description:In vitro inhibition of Histamine H2 receptor by measuring its ability to block the histamine-stimulated adenylate cyclase of guinea pig hippocampal h...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 9.80nMAssay Description:muscarinic acetylcholine receptor M3-antagonistic activity on the isolated guinea pig ileum determined by Schild plot.More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
Affinity DataKi: 12nMAssay Description:Inhibition of [125I]APT binding to histamine H2 receptor in guinea pig cerebral membranes.More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Binding affinity to human H2R expressing Sf9 cells incubated for 60 mins by microbeta scintillation counter methodMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [125I]Aminopotentidine from human recombinant histamine H2 receptor expressed in CHOK1 cells after 2 hrsMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in baculovirus infected Sf9 cells incubated for 60 mins by scintillation count...More data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Queen'S Medical Centre
Curated by PDSP Ki Database
Queen'S Medical Centre
Curated by PDSP Ki Database
TargetHistamine H2 receptor(Homo sapiens (Human))
National Institute Of Mental Health
Curated by ChEMBL
National Institute Of Mental Health
Curated by ChEMBL
Affinity DataKi: 22nMAssay Description:Displacement of [3H]UR-DE257 from Gsalphas-coupled human H2R expressed in Sf9 cell membranes by competitive binding assayMore data for this Ligand-Target Pair