Affinity DataIC50: 1nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Concentration of test compound required for inhibition of binding of rHsp90 in MCF-7 cell lysateMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Concentration of test compound required for inhibition of binding of rHsp90 in MCF-7 cell lysateMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human HSP90 in HCT116 cells expressing Her2 gene assessed as degradation of Her2 after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HSP90 in human SKBR3 cells assessed as induction of Her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Concentration of test compound required for half-maximal inhibition of binding of Heat shock 90 KD protein by MCF-7 cell lysate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Concentration of test compound required for inhibition of binding of rHsp90 in MCF-7 cell lysateMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Concentration of test compound required for inhibition of binding of rHsp90 in MCF-7 cell lysateMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Concentration of test compound required for inhibition of binding of rHsp90 in MCF-7 cell lysateMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of geldanamycin-based probe binding to HSP90 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as her2 degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of Hsp90 in human MDA-MB-231 cells assessed as Akt degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Hsp90 in human H1299 cells after 24 hrs by Akt luminex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human HSP90 using BODIPY labelled geldanamycin as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of FITC-geldanamycin binding to human His-tagged HSP90alpha N-terminal domain (1 to 236 residues) expressed in Escherichia coli BL21star (...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Hsp90 in human SKBR3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Hsp90 in human A2058 cells assessed as Akt degradationMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of biotinylated geldanamycin from human His-tagged Hsp90 by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as HER2 degradation by cell-based assayMore data for this Ligand-Target Pair