Compile Data Set for Download or QSAR
Report error Found 283 of ic50 for UniProtKB: P35439
LigandPNGBDBM50140341(6-(3-(4-(4-fluorobenzyl)piperidin-1-yl)prop-1-ynyl...)
Affinity DataIC50: 2nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50091636(5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 3nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50140339(5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 4nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50066544(4-[2-(5-Phenyl-pentylamino)-ethyl]-phenol | CHEMBL...)
Affinity DataIC50: 8nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50080029(CHEMBL305195 | 4-[(1R,2S)-3-(4-Benzyl-piperidin-1-...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity against rat 1A/2B subtype of N-methyl-D-aspartate (NMDA) receptor in xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080029(CHEMBL305195 | 4-[(1R,2S)-3-(4-Benzyl-piperidin-1-...)
Affinity DataIC50: 9nMAssay Description:Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080029(CHEMBL305195 | 4-[(1R,2S)-3-(4-Benzyl-piperidin-1-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of rat NMDA receptor NR1C/NR2B subunit expressed in Xenopus laevis oocytes after 2 days by two-electrode voltage-clamp electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50140333(5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 9nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50369783(CHEMBL1203902)
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50085922(4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50091635(5-{3-[4-(3-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 14nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50066538(4-[3-(4-Phenyl-butylamino)-propyl]-phenol | CHEMBL...)
Affinity DataIC50: 15nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50140331(6-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 15nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50085933(4-[1-(5-Phenyl-pentyl)-pyrrolidin-3-yl]-phenol | C...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50080029(CHEMBL305195 | 4-[(1R,2S)-3-(4-Benzyl-piperidin-1-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat NMDA receptor NR1F/NR2B subunit expressed in Xenopus laevis oocytes after 2 days by two-electrode voltage-clamp electrophysiologica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50038168(7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...)
Affinity DataIC50: 18nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50369786(CHEMBL1201889)
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50085927(4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...)
Affinity DataIC50: 19nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50140334(5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 19nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50066538(4-[3-(4-Phenyl-butylamino)-propyl]-phenol | CHEMBL...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity against rat 1A/2B subtype of N-methyl-D-aspartate (NMDA) receptor in xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50081743(1-[4-(1H-Imidazol-4-yl)-but-3-ynyl]-4-(4-methyl-be...)
Affinity DataIC50: 20nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50140327(6-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 20nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50091629(5-{3-[4-(4-Fluoro-benzyl)-4-hydroxy-piperidin-1-yl...)
Affinity DataIC50: 21nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50369791(CHEMBL1202296)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50082020(2-Chloro-N-{2-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataIC50: 24nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50140335(6-{3-[4-(4-Fluoro-benzyl)-4-hydroxy-piperidin-1-yl...)
Affinity DataIC50: 24nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50079386(4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol | 4-...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50085929(4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50079389(4-{2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-ethoxy}-...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50081749(4-(4-Chloro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50140325(6-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 31nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082024(2-{2-[3-(7-Chloro-4-hydroxy-2-oxo-1,2-dihydro-quin...)
Affinity DataIC50: 32nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50066547(4-[2-(6-Phenyl-hexylamino)-ethyl]-phenol | CHEMBL4...)
Affinity DataIC50: 35nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50081748(4-Benzyl-1-[4-(1H-imidazol-4-yl)-but-3-ynyl]-piper...)
Affinity DataIC50: 37nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50082027(2-Chloro-N-{3-[3-(7-chloro-4-hydroxy-2-oxo-1,2-dih...)
Affinity DataIC50: 39nMAssay Description:Antagonistic activity for suppression of membrane current response elicited by fixed concentration of glycine and glutamate in Xenopus oocyte express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50079385(1-[2-(4-Hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50066539(4-[2-(4-Phenyl-butylamino)-ethyl]-phenol | CHEMBL1...)
Affinity DataIC50: 43nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50066546(4-[3-(5-Phenyl-pentylamino)-propyl]-phenol | CHEMB...)
Affinity DataIC50: 45nMAssay Description:Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
LigandPNGBDBM50079388(4-{2-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-ethoxy}-...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50078318(2-(4-Phenyl-butyl)-2,3,4,9-tetrahydro-1H-beta-carb...)
Affinity DataIC50: 50nMAssay Description:Antagonist activity against rat 1A/2B subtype of N-methyl-D-aspartate (NMDA) receptor in xenopus oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50081753(4-(4-Fluoro-benzyl)-1-[4-(1H-imidazol-4-yl)-but-3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50140336(6-{3-[4-(4-Fluoro-benzyl)-4-hydroxy-piperidin-1-yl...)
Affinity DataIC50: 51nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50140340(5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50: 56nMAssay Description:Binding affinity against NR1A/2B receptor in rat brains by [3H]ifenprodil displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50304085(N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methyls...)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at wild type rat NR1/NR2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced curren...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50304085(N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methyls...)
Affinity DataIC50: 57nMAssay Description:Antagonist activity at rat recombinant NR1/NR2B receptor expressed in frog oocytes assessed as inhibition of glutamate/glycine-induced current by two...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
LigandPNGBDBM50085921(4-[1-(3-Phenyl-propyl)-piperidin-4-ylmethyl]-pheno...)
Affinity DataIC50: 59nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50369784(CHEMBL1202295)
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
LigandPNGBDBM50032651(1-[(1S,2S)-2-Hydroxy-2-(4-hydroxy-phenyl)-1-methyl...)
Affinity DataIC50: 73nMAssay Description:Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50081747(4-Benzyl-1-[4-(1H-pyrazol-4-yl)-but-3-ynyl]-piperi...)
Affinity DataIC50: 74nMAssay Description:Inhibition of NMDA response at NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50369782(CHEMBL1203909)
Affinity DataIC50: 74nMAssay Description:Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
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