Affinity DataKi: 4.91E+4nM ΔG°: -25.0kJ/moleT: 2°CAssay Description:In kinetic assay, the TP enzyme (0.058 U/well) was incu- bated with different concentrations of inhibitor (0.5¿0.001 mM) for 10 min at 30 C. The rea...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory activity against Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Thymidine phosphorylase from Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase using thymidine 5' mono phosphate as substrate after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Escherichia coli (Enterobacteria))
Comsats Institute of Information Technology
Comsats Institute of Information Technology
Affinity DataIC50: 3.87E+4nMpH: 7.4Assay Description:Briefly, a total reaction mixture of 200 µl contained 145 µl of potassium phosphate buffer (pH 7.4), 30 µl of enzyme at concentration 0.05 and 0.002 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.87E+4nMpH: 7.4 T: 2°CAssay Description:The Thymidine phosphorylase/PD-ECGF (E. coli) activity was determined by measuring the absorbance at 290 nm spectrophotometrically. In brief, total r...More data for this Ligand-Target Pair
Affinity DataIC50: 3.87E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 3.93E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against thymidine phosphorylase of Escherichia coliMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin) using thymidine as substrate after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMpH: 7.0Assay Description:TP inhibition assay was performed spectrophotometrically. The method of Bera et al. was followed with slight modifications. Reaction mixture of 200 µ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMT: 2°CAssay Description:TP inhibition assay was performed spectrophotometrically in 96-well plate. The method of Bera et al. was followed with slight modifications [Bera et ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of human recombinant thymidine phosphorylase expressed in Escherichia coli using thymidine as substrate after 4 to 20 mins by spectrophoto...More data for this Ligand-Target Pair
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of human recombinant thymidine phosphorylase expressed in Escherichia coli assessed as conversion of thymidine to thymine after 4 to 20 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair