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Found 73 with Last Name = 'grosfeld' and Initial = 'd'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253155(CHEMBL492266 | N-Cyclopropyl-4-methyl-3-(4-(1-meth...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(CHEMBL493708 | N-Cyclopropyl-4-methyl-3-(1-((R)-2,...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  1nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(CHEMBL494272 | N-Cyclopropyl-4-methyl-3-(1-(4-morp...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252740(CHEMBL494270 | N-Cyclopropyl-4-methyl-3-(1-((2-(4-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)
Affinity DataIC50:  10.5nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253155(CHEMBL492266 | N-Cyclopropyl-4-methyl-3-(4-(1-meth...)
Affinity DataIC50:  41nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)
Affinity DataIC50:  122nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  149nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)
Affinity DataIC50:  162nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50:  182nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)
Affinity DataIC50:  421nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(CHEMBL493708 | N-Cyclopropyl-4-methyl-3-(1-((R)-2,...)
Affinity DataIC50:  505nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(CHEMBL494272 | N-Cyclopropyl-4-methyl-3-(1-(4-morp...)
Affinity DataIC50:  529nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)
Affinity DataIC50:  629nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252739(CHEMBL494072 | N-Cyclopropyl-4-methyl-3-(2-((2-(4-...)
Affinity DataIC50:  788nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  954nMAssay Description:Inhibition of Lyn (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252740(CHEMBL494270 | N-Cyclopropyl-4-methyl-3-(1-((2-(4-...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(CHEMBL493708 | N-Cyclopropyl-4-methyl-3-(1-((R)-2,...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  2.01E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(CHEMBL494272 | N-Cyclopropyl-4-methyl-3-(1-(4-morp...)
Affinity DataIC50:  3.04E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)
Affinity DataIC50:  3.61E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(CHEMBL494272 | N-Cyclopropyl-4-methyl-3-(1-(4-morp...)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(CHEMBL493708 | N-Cyclopropyl-4-methyl-3-(1-((R)-2,...)
Affinity DataIC50:  4.39E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  4.83E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252740(CHEMBL494270 | N-Cyclopropyl-4-methyl-3-(1-((2-(4-...)
Affinity DataIC50:  5.15E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  5.52E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)
Affinity DataIC50:  5.95E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(CHEMBL493708 | N-Cyclopropyl-4-methyl-3-(1-((R)-2,...)
Affinity DataIC50:  6.05E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50:  6.29E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(CHEMBL492265 | N-Cyclopropyl-4-methyl-3-(1-(2-meth...)
Affinity DataIC50:  6.63E+3nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50:  7.77E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50: >8.33E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252779(CHEMBL494469 | N-Cyclopropyl-4-methyl-3-(1-((3S)-3...)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253152(CHEMBL493708 | N-Cyclopropyl-4-methyl-3-(1-((R)-2,...)
Affinity DataIC50:  9.49E+3nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(CHEMBL494272 | N-Cyclopropyl-4-methyl-3-(1-(4-morp...)
Affinity DataIC50:  9.69E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50253153(CHEMBL495330 | N-Cyclopropyl-4-methyl-3-(1-phenyl-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252782(CHEMBL493671 | N-Cyclopropyl-4-methyl-3-(1-((S)-2,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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