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TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255695(4-(2,3-dichlorophenylamino)-7-(2-(dimethylamino)et...)
Affinity DataIC50: 3nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255697(4-(2,3-dichlorophenylamino)-6-(2-(dimethylamino)et...)
Affinity DataIC50: 3nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 5nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255375(4-(2,3-dichlorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255698(4-(2,3-dichlorophenylamino)-7-ethoxy-6-(2-(piperid...)
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255588(4-(3-chloro-4-fluorophenylamino)-6-methoxy-7-(3-(4...)
Affinity DataIC50: 7nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255645(4-(2,3-dichlorophenylamino)-7-methoxy-6-(2-(piperi...)
Affinity DataIC50: 7nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255744(4-(2,4-difluorophenylamino)-6-(2-(dimethylamino)et...)
Affinity DataIC50: 7nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255746(4-(2,4-difluorophenylamino)-7-methoxy-6-(2-morphol...)
Affinity DataIC50: 7nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255145(4-(2-fluorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50: 9nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255464(4-(3,4-dichlorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 9nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255419(4-(2-fluoro-4-methylphenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255586(4-(3-chloro-4-fluorophenylamino)-7-(2-((2-hydroxye...)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255643(4-(3-chloro-4-fluorophenylamino)-7-methoxy-6-(3-(4...)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255514(4-(3-chloro-4-fluorophenylamino)-7-(2-(dimethylami...)
Affinity DataIC50: 12nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255372(4-(3-chloro-2-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 13nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255466(4-(2-fluoro-5-methylphenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 13nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255642(4-(3-chloro-4-fluorophenylamino)-7-methoxy-6-(2-(p...)
Affinity DataIC50: 13nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255465(4-(2,5-difluorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255696(4-(2,3-dichlorophenylamino)-6-methoxy-7-(2-(piperi...)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255463(4-(3-chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 16nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255515(4-(3-chloro-4-fluorophenylamino)-7-(2-(cyclopropyl...)
Affinity DataIC50: 17nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255587(4-(3-chloro-4-fluorophenylamino)-6-methoxy-7-(2-(p...)
Affinity DataIC50: 17nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255259(4-(3-chlorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50: 18nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255420(4-(4-chloro-2-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 18nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255516(4-(3-chloro-4-fluorophenylamino)-6-methoxy-7-(2-((...)
Affinity DataIC50: 18nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255255(4-(2-chlorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50: 22nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255513(4-(3,5-dichlorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 22nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255745(4-(2,4-difluorophenylamino)-7-methoxy-6-(2-(piperi...)
Affinity DataIC50: 22nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255747(4-(2,4-difluorophenylamino)-7-(2-(dimethylamino)et...)
Affinity DataIC50: 23nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255418(4-(2,4-difluorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255371(4-(2,3-difluorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 26nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255421(4-(3,4-difluorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 28nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255374(4-(3-chloro-2-methylphenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 29nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255317(4-(4-fluorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50: 30nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256750(N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(tr...)
Affinity DataIC50: 31nMAssay Description:Inhibition of PDGFRbMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255318(4-(4-chlorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50: 31nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255373(4-(2,3-dimethylphenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 31nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255258(4-(3-fluorophenylamino)-6,7-dimethoxyquinoline-3-c...)
Affinity DataIC50: 33nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255256(4-(2-bromophenylamino)-6,7-dimethoxyquinoline-3-ca...)
Affinity DataIC50: 36nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255316(6,7-dimethoxy-4-(m-tolylamino)quinoline-3-carboxam...)
Affinity DataIC50: 38nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255319(6,7-dimethoxy-4-(4-methoxyphenylamino)quinoline-3-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255257(6,7-dimethoxy-4-(o-tolylamino)quinoline-3-carboxam...)
Affinity DataIC50: 52nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50240907(4-(2,4-dichlorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 52nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255589(4-(3-chloro-4-fluorophenylamino)-7-(2-(4-hydroxypi...)
Affinity DataIC50: 80nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255320(4-(4-(dimethylamino)phenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255467(4-(3,5-difluorophenylamino)-6,7-dimethoxyquinoline...)
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50255098(4-(2-chloro-4-fluorophenylamino)-6,7-dimethoxyquin...)
Affinity DataIC50: 200nMAssay Description:Inhibition of His-tagged CSF1R catalytic domain expressed in baculovirus by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50256724(N-(5-chloropyridin-3-yl)-5-(3-(2-cyanopropan-2-yl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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